DNA-binding proteins and uses thereof
PD Gregory, JC Miller, D Paschon, EJ Rebar… - US Patent …, 2013 - Google Patents
2011-08-17 Assigned to SANGAMO BIOSCIENCES, INC. reassignment SANGAMO
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Methods and compositions for targeted cleavage and recombination
F Urnov, MC Holmes, JC Miller, CO Pabo - US Patent 7,888,121, 2011 - Google Patents
2005-03-29 Assigned to SANGAMO BIOSCIENCES, INC. reassignment SANGAMO
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Targeted chromosomal mutagenasis using zinc finger nucleases
D Carroll, M Bibikova, GN Drews, KG Golic… - US Patent …, 2012 - Google Patents
The present invention provides for a method or methods of targeted genetic recombination
or mutagenesis in a host cell or organism, and compositions useful for carrying out the …
or mutagenesis in a host cell or organism, and compositions useful for carrying out the …
Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
M Liljedahl, S Aspland, D Segal - US Patent App. 10/395,816, 2003 - Google Patents
Embodiments relate to methods of generating a genetically modified cell. The methods can
include providing a primary cell containing an endogenous chromosomal target DNA …
include providing a primary cell containing an endogenous chromosomal target DNA …
Use of chimeric nucleases to stimulate gene targeting
D Baltimore, M Porteus - US Patent 9,447,434, 2016 - Google Patents
Gene targeting is a technique to introduce genetic change into one or more specific
locations in the genome of a cell. For example, gene targeting can introduce genetic change …
locations in the genome of a cell. For example, gene targeting can introduce genetic change …
Modulation of endogenous gene expression in cells
CC Case, F Urnov, A Lai, A Snowden, S Tan… - US Patent …, 2005 - Google Patents
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Ladner et al. 5,198.346 A 3/1993 Ladner et al. 5,223,409 A 6/1993 Ladner et al. 5.243, 041 …
Regulation of endogenous gene expression in cells using zinc finger proteins
GN Cox III, CC Case, SP Eisenberg, EE Jarvis… - US Patent …, 2005 - Google Patents
The present application demonstrates for the first time that ZFPS can be used to regulate
expression of an endogenous cellular gene that is present in its native chromatin environ …
expression of an endogenous cellular gene that is present in its native chromatin environ …
Methods and compositions for targeted single-stranded cleavage and targeted integration
J Wang - US Patent 8,703,489, 2014 - Google Patents
US8703489B2 - Methods and compositions for targeted single-stranded cleavage and
targeted integration - Google Patents US8703489B2 - Methods and compositions for targeted …
targeted integration - Google Patents US8703489B2 - Methods and compositions for targeted …
Targeted deletion of cellular DNA sequences
D Guschin, MC Holmes - US Patent 8,409,861, 2013 - Google Patents
Related US Application Data (63) Continuation-in-part of application No. 10/912.932, filed
on Aug. 6, 2004, now Pat. No. 7,888,121.(60) Provisional application No. 60/649,515, filed …
on Aug. 6, 2004, now Pat. No. 7,888,121.(60) Provisional application No. 60/649,515, filed …
Regulation of endogenous gene expression in cells using zinc finger proteins
GN Cox III, CC Case, SP Eisenberg, EE Jarvis… - US Patent …, 2004 - Google Patents
US6824978B1 - Regulation of endogenous gene expression in cells using zinc finger proteins
- Google Patents US6824978B1 - Regulation of endogenous gene expression in cells using …
- Google Patents US6824978B1 - Regulation of endogenous gene expression in cells using …