Glycolipids are present on the surfaces of all living cells and thereby represent targets for
many protein receptors, such as lectins. Understanding the interactions between lectins and …

Abstract Methyl 5-thio-α-d-galactopyranoside was synthesized and found to have a more
favorable enthalpy of binding to Jacalin than methyl α-d-galactopyranoside, which is …

Lectins are versatile proteins that specifically recognize and interact with sugar moieties
expressed on the cell surface. The potential of lectin in drug targeting and delivery has …

Crystal structures of jacalin in complex with GlcNAc β‐(1, 3) Gal‐β‐OMe and Gal β‐(1, 3) Gal‐
β‐OMe have been determined. The binding of the ligands to jacalin is similar to that of …

Earnest attempts at initiating macromolecular crystallography, which is central to modern
biology, started in India in the 1970s. The most important component of the efforts was on …

Frutalin (FTL) is a multiple-binding lectin belonging to the jacalin-related lectin (JRL) family
and derived from Artocarpus incisa (breadfruit) seeds. This lectin specifically recognizes and …

Frutalin (FTL) is a multiple-binding lectin belonging to the jacalin-related lectin (JRL) family
and derived from Artocarpus incisa (breadfruit) seeds. This lectin specifically recognizes and …

Thioglycosides and thiosugars both have a long history in bioorganic and medicinal
chemistry. As presented in Chapter 1, thioglycosides and thiosugars are well-documented …

Abstract The genus Artocarpus (Moraceae) comprises about 60 species of evergreen and
deciduous trees, including those of notable value as sources of edible fruit and uses in folk …

This thesis consists of two parts. The first part is concerned with further structural and related
studies of jacalin, one of the two lectins found in jack fruit seeds. The second part deals with …