Designer exosomes: a new platform for biotechnology therapeutics
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
Paracrine mechanisms of mesenchymal stromal cells in angiogenesis
S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs
G Qiu, G Zheng, M Ge, J Wang, R Huang… - Stem Cell Research & …, 2018 - Springer
Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
Immunomodulatory effects of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles in rheumatoid arthritis
H Liu, R Li, T Liu, L Yang, G Yin, Q Xie - Frontiers in Immunology, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints and other
organs for which there is currently no effective treatment. Mesenchymal stem cells (MSCs) …
organs for which there is currently no effective treatment. Mesenchymal stem cells (MSCs) …
Functional proteins of mesenchymal stem cell-derived extracellular vesicles
G Qiu, G Zheng, M Ge, J Wang, R Huang… - Stem cell research & …, 2019 - Springer
Extracellular vesicles (EVs) contain proteins, microRNAs, mRNAs, long non-coding RNAs,
and phospholipids, and are a novel mechanism of intercellular communication. It has been …
and phospholipids, and are a novel mechanism of intercellular communication. It has been …
Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels
Abstract Background Extracellular vesicles (EVs) are released by nearly every cell type and
have attracted much attention for their ability to transfer protein and diverse RNA species …
have attracted much attention for their ability to transfer protein and diverse RNA species …
[HTML][HTML] Mesenchymal stem cell-derived exosomes as drug delivery vehicles in disease therapy
W Zhao, K Li, L Li, R Wang, Y Lei, H Yang… - International Journal of …, 2024 - mdpi.com
Exosomes are small vesicles containing proteins, nucleic acids, and biological lipids, which
are responsible for intercellular communication. Studies have shown that exosomes can be …
are responsible for intercellular communication. Studies have shown that exosomes can be …
Extracellular vesicles: Interplay with the extracellular matrix and modulated cell responses
A Al Halawani, SM Mithieux, GC Yeo… - International journal of …, 2022 - mdpi.com
The discovery that cells secrete extracellular vesicles (EVs), which carry a variety of
regulatory proteins, nucleic acids, and lipids, has shed light on the sophisticated manner by …
regulatory proteins, nucleic acids, and lipids, has shed light on the sophisticated manner by …
[HTML][HTML] Mesenchymal stem cell exosomes in bone regenerative strategies—a systematic review of preclinical studies
The ability of bone for regeneration has long been recognized. However, once beyond a
critical size, spontaneous regeneration of bone is limited. Several studies have focused on …
critical size, spontaneous regeneration of bone is limited. Several studies have focused on …
Angiogenic effects and crosstalk of adipose-derived mesenchymal stem/stromal cells and their extracellular vesicles with endothelial cells
S Rautiainen, T Laaksonen, R Koivuniemi - International Journal of …, 2021 - mdpi.com
Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …