Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature

N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

Ketamine induces ferroptosis of liver cancer cells by targeting lncRNA PVT1/miR-214-3p/GPX4

GN He, NR Bao, S Wang, M Xi, TH Zhang… - Drug design …, 2021 - Taylor & Francis
Background Liver cancer ranks the top four malignant cancer type worldwide, which needs
effective and safe treatment. Ferroptosis is a novel form of regulated cell death driven by iron …

[HTML][HTML] Beneficial Effects of Astragalus membranaceus (Fisch.) Bunge Extract in Controlling Inflammatory Response and Preventing Asthma Features

D D'Avino, I Cerqua, H Ullah, M Spinelli… - International Journal of …, 2023 - mdpi.com
Astragalus membranaceus (Fisch.) Bunge root is used as herbal medicine for its
immunomodulating activities in Chinese medicine. Recently, beneficial properties of A …

[HTML][HTML] Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae

F Martinelli, A Perrone, S Yousefi, A Papini… - Molecules, 2021 - mdpi.com
Hawthorn (Crataegus monogyna Jacq.) is a wild edible fruit tree of the genus Crataegus,
one of the most interesting genera of the Rosaceae family. This review is the first to consider …

[HTML][HTML] Resveratrol modulates chemosensitisation to 5-FU via β1-integrin/HIF-1α Axis in CRC tumor microenvironment

A Brockmueller, S Girisa, AB Kunnumakkara… - International Journal of …, 2023 - mdpi.com
Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-
FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to …

[HTML][HTML] Therapeutic potential of camel milk exosomes against HepaRG cells with potent apoptotic, anti-inflammatory, and anti-angiogenesis effects for colostrum …

AM El-Kattawy, O Algezawy, MY Alfaifi… - Biomedicine & …, 2021 - Elsevier
This study aimed to evaluate and compare the therapeutic effect of camel milk exosomes
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …

[HTML][HTML] Targeting ROS/NF-κB signaling pathway by the seedless black Vitis vinifera polyphenols in CCl4-intoxicated kidney, lung, brain, and spleen in rats

NH Habashy, AS Kodous, MM Abu-Serie - Scientific reports, 2021 - nature.com
Carbon tetrachloride (CCl4) is an abundant environmental pollutant that can generate free
radicals and induce oxidative stress in different human and animal organs like the kidney …

Xanthosine, a purine glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK …

SA Ahmed, P Sarma, SR Barge, D Swargiary… - Chemico-Biological …, 2023 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2DM) is characterized by hepatic insulin resistance,
which results in increased glucose production and reduced glycogen storage in the liver …

[HTML][HTML] 4-OI attenuates carbon tetrachloride-induced hepatic injury via regulating oxidative stress and the inflammatory response

R Li, W Yang, Y Yin, X Ma, P Zhang… - Frontiers in pharmacology, 2021 - frontiersin.org
The liver is an important metabolic organ, and acute liver injury (ALI) is potentially lethal.
Itaconate, a metabolic intermediate from the tricarboxylic acid cycle, showed emerging anti …