Histopathological grading of epithelial dysplasia remains the principal laboratory method for
assessing the risk of malignant transformation in oral potentially malignant disorders …

Among oral diseases, oral cancer is a critical health issue due to its life-threatening
potential. Globocan, in its 2020 report, estimated∼ 0.37 million new cases of oral cancer …

Leukoplakia and erythroplakia are two entities under the moniker of “oral potentially
malignant disorders” that are highly associated with the presence of oral epithelial dysplasia …

The ability to predict malignant transformation in oral potentially malignant disorders would
inform targeted treatment, provide prognostic information and allow secondary prevention …

Background This prospective observational study investigated the determinants of malignant
transformation (MT) in localized oral leukoplakia (OL) and proliferative verrucous …

Objective Proliferative verrucous leukoplakia (PVL) has high rates of malignant
transformation into oral squamous cell carcinoma (OSCC), but the clinical and evolutionary …

Objectives To explore the pathophysiology of proliferative verrucous leukoplakia, a rare oral
disorder that exhibits high rates of recurrence and malignant transformation, through a …

Objective Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia with a
relatively high transformation rate resulting in oral squamous cell carcinoma (OSCC) …

Oral leukoplakia (OL) is the most common oral potentially malignant disorder, with a global
prevalence of 2%‐3%, variable malignant transformation rate and incompletely understood …

Objective This study aimed to evaluate prognostic outcomes of PVL‐derived oral squamous
cell carcinomas (P‐OSCC) based on recurrence, new primary tumour, metastasis and …