High-grade neuroendocrine neoplasms are a rare disease entity and account for
approximately 10% of all neuroendocrine neoplasms. Because of their rarity, there is an …

Neuroendocrine tumors (NETs) are rare and sporadic in origin. They can occur in almost
every organ; however, the majority are gastroenteropancreatic (GEP) in 61%, bronchial in …

Grade 3 neuroendocrine neoplasms (NEN G3) are high-grade (Ki-67 index> 20%)
neuroendocrine malignancies that comprise both rapidly proliferating, well-differentiated …

The classification and management of neuroendocrine neoplasms (NENs) arising in the
tubular gastrointestinal (GI) tract and pancreas have significantly evolved over the last …

Peptide receptor radionuclide therapy (PRRT) has been primarily studied in low and
intermediate‐grade digestive neuroendocrine tumors (NET G1‐G2). The documentation of a …

High-grade (HG) pancreatic neuroendocrine neoplasms (PAN-NENs) are aggressive and
have a poor prognosis. Yet, our understanding and treatment approaches for these tumors …

摘要神经内分泌肿瘤(NEN) 是一种罕见的高异质性肿瘤, 起源于肽能神经元和神经内分泌细胞,
可发生在支气管, 肺部和胃肠, 胰腺等多种部位, 我国以胰腺神经内分泌肿瘤(pNEN) 最为多见 …

Abstract Purpose of Review Gastroenteropancreatic NEN (GEP-NEN) are group of
malignancies with significant clinical, anatomical and molecular heterogeneity. High-grade …

The over-arching concept of “theranostics” has been described by various groups (Bodei et
al., Nat Rev Clin Oncol 19: 534–550, 2022, Baum and Kulkarni, Theranostics 2: 437–447 …

Objectives: This study aimed to evaluate the clinical outcomes, including progression-free
survival (PFS), overall survival (OS), Objective Response Rate (ORR), and Disease Control …