Perianal fistulising Crohn's disease is an aggressive disease phenotype that can have a
substantial detrimental impact on patients' quality of life. Current biological understanding of …

Enterocutaneous fistula is any communication between bowel and skin or atmosphere
outside the body. It can be classified by various means by etiology, organ of origin, etc …

Background & Aims Efficacy of upadacitinib, an oral Janus kinase inhibitor, for moderate-to-
severe Crohn's disease was demonstrated in phase 3 induction (U-EXCEL, U-EXCEED) …

Background Translational data suggest a potential role of hyperbaric oxygen therapy
(HBOT) in a subset of patients with inflammatory bowel disease (IBD). We performed a …

BACKGROUND: Crohn's disease perianal fistulas are often resistant to standard anti–tumor
necrosis factor-α therapies. Mesenchymal stem cell–derived exosomes are extracellular …

Background: Data on the performance of newer biologics in patients with fistulizing Crohn's
disease (CD) are limited. Objective: Our study's objective was to evaluate the response to …

BACKGROUND Patients with Crohn's disease (CD) are at risk of developing complications
such as perianal fistulas. Patients with Crohn's perianal fistulas (CPF) are affected by fecal …

The treatment of perianal fistulas remains a clinical challenge despite the significant
advances that have been made in the management of luminal inflammatory bowel disease …

Crohn's disease (CD) is a chronic immune-mediated inflammatory condition caused by the
loss of mucosal tolerance toward the commensal microbiota. On average, 29.5% and 42.7 …

Background Perianal fistula (PAF) is a disabling complication of Crohn's disease (CD) which
greatly impacts the quality of life. To address a scarcity of data in Asian populations, we …