Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …

Intracerebral haemorrhage is inadequately controlled by current treatments, requiring new
solutions to improve the prognosis. Following the primary injury, a proinflammatory cascade …

As extremely sensitive immune cells, microglia act as versatile watchdogs of the central
nervous system (CNS) that tightly control tissue homeostasis. Therefore, microglial activation …

The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …

Post-stroke Epilepsy (PSE) is one of the most common forms of acquired epilepsy,
especially in the elderly population. As people get increasingly older, the number of stroke …

Background and purpose Cerebral small vessel disease (CSVD) is a clinically commonly-
seen slow-progressing cerebral vascular disease. As a classic Chinese formula for the …

Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …

Multiple sclerosis (MS) is a complex neurological condition that involves both inflammatory
demyelinating and neurodegenerative components. MS research and treatments have …