[HTML][HTML] Quinolones: mechanism, lethality and their contributions to antibiotic resistance
NG Bush, I Diez-Santos, LR Abbott, A Maxwell - Molecules, 2020 - mdpi.com
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times.
They have enjoyed over 30 years of clinical usage and become essential tools in the …
They have enjoyed over 30 years of clinical usage and become essential tools in the …
Multidrug efflux pumps: structure, function and regulation
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …
throughout the world and threaten to become untreatable. The origins of resistance are …
Molecular mechanisms of antibiotic resistance
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly
common and are causing a global health crisis. Antibiotic resistance is encoded by several …
common and are causing a global health crisis. Antibiotic resistance is encoded by several …
The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria
The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …
Drug resistant Tuberculosis: A review
JL Khawbung, D Nath, S Chakraborty - … immunology, microbiology and …, 2021 - Elsevier
Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …
counter attack of TB worldwide. However, when it was known that TB can be cured …
[HTML][HTML] Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success
LS Redgrave, SB Sutton, MA Webber… - Trends in microbiology, 2014 - cell.com
Quinolone and fluoroquinolone antibiotics are potent, broad-spectrum agents commonly
used to treat a range of infections. Resistance to these agents is multifactorial and can be via …
used to treat a range of infections. Resistance to these agents is multifactorial and can be via …
Acinetobacter baumannii Efflux Pumps and Antibiotic Resistance
SN Abdi, R Ghotaslou, K Ganbarov… - Infection and drug …, 2020 - Taylor & Francis
Acinetobacter baumannii is a nosocomial pathogen and gram-negative coccobacillus that is
responsible for opportunistic infections, pneumonia, and infections of the urinary tract …
responsible for opportunistic infections, pneumonia, and infections of the urinary tract …
Discovery and development of new antibacterial drugs: learning from experience?
N Jackson, L Czaplewski… - Journal of Antimicrobial …, 2018 - academic.oup.com
Antibiotic (antibacterial) resistance is a serious global problem and the need for new
treatments is urgent. The current antibiotic discovery model is not delivering new agents at a …
treatments is urgent. The current antibiotic discovery model is not delivering new agents at a …
[HTML][HTML] Antibiotic resistance in Vibrio cholerae: understanding the ecology of resistance genes and mechanisms
The unique genetic makeup and remarkable competency of Vibrio cholerae are the key
factors that help the cholera pathogen adapt rapidly to adverse environmental conditions …
factors that help the cholera pathogen adapt rapidly to adverse environmental conditions …
Quinolones: from antibiotics to autoinducers
S Heeb, MP Fletcher, SR Chhabra… - FEMS microbiology …, 2011 - academic.oup.com
Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …
variety of quinolone compounds have been discovered, several of which possess …