Gene duplication as a mechanism of genomic adaptation to a changing environment
FA Kondrashov - Proceedings of the Royal Society B …, 2012 - royalsocietypublishing.org
A subject of extensive study in evolutionary theory has been the issue of how neutral,
redundant copies can be maintained in the genome for long periods of time. Concurrently …
redundant copies can be maintained in the genome for long periods of time. Concurrently …
β-Defensins: farming the microbiome for homeostasis and health
KG Meade, C O'Farrelly - Frontiers in Immunology, 2019 - frontiersin.org
Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …
protection against disease. Although bacteria are the most abundant component of …
[HTML][HTML] Resequencing 302 wild and cultivated accessions identifies genes related to domestication and improvement in soybean
Understanding soybean (Glycine max) domestication and improvement at a genetic level is
important to inform future efforts to further improve a crop that provides the world's main …
important to inform future efforts to further improve a crop that provides the world's main …
Assembly of a pangenome for global cattle reveals missing sequences and novel structural variations, providing new insights into their diversity and evolutionary …
Y Zhou, L Yang, X Han, J Han, Y Hu, F Li… - Genome …, 2022 - genome.cshlp.org
A cattle pangenome representation was created based on the genome sequences of 898
cattle representing 57 breeds. The pangenome identified 83 Mb of sequence not found in …
cattle representing 57 breeds. The pangenome identified 83 Mb of sequence not found in …
The sheep genome illuminates biology of the rumen and lipid metabolism
Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and
represent a distinct class of animals that have a specialized digestive organ, the rumen, that …
represent a distinct class of animals that have a specialized digestive organ, the rumen, that …
Genomes of the banyan tree and pollinator wasp provide insights into fig-wasp coevolution
Banyan trees are distinguished by their extraordinary aerial roots. The Ficus genus includes
species that have evolved a species-specific mutualism system with wasp pollinators. We …
species that have evolved a species-specific mutualism system with wasp pollinators. We …
[HTML][HTML] NLR diversity, helpers and integrated domains: making sense of the NLR IDentity
E Baggs, G Dagdas, KV Krasileva - Current opinion in plant biology, 2017 - Elsevier
Highlights•Plant NLR immune receptors are rapidly diversifying modular proteins.•There is a
vast diversity in NLR copy number and allelic variation across species.•NLRs are sensors of …
vast diversity in NLR copy number and allelic variation across species.•NLRs are sensors of …
DbVar and DGVa: public archives for genomic structural variation
I Lappalainen, J Lopez, L Skipper… - Nucleic acids …, 2012 - academic.oup.com
Much has changed in the last two years at DGVa (http://www. ebi. ac. uk/dgva) and dbVar
(http://www. ncbi. nlm. nih. gov/dbvar). We are now processing direct submissions rather …
(http://www. ncbi. nlm. nih. gov/dbvar). We are now processing direct submissions rather …
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle
Inbred animals were historically chosen for genome analysis to circumvent assembly issues
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
Copy number polymorphism in plant genomes
Copy number variants (CNVs) are genomic rearrangements resulting from gains or losses of
DNA segments. Typically, the term refers to rearrangements of sequences larger than 1 kb …
DNA segments. Typically, the term refers to rearrangements of sequences larger than 1 kb …