The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …

Highlights•SynBio needs chassis with superior genetic, biochemical, and physiological
traits.•Environmental bacteria are endowed with many advantageous metabolic properties.• …

Future manufacturing will focus on new, improved products as well as on new and
enhanced production methods. Recent biotechnological and scientific advances, such as …

Glycyrrhetinic acid (GA) and its precursor, 11-oxo-β-amyrin, are typical triterpenoids found in
the roots of licorice, a traditional Chinese medicinal herb that exhibits diverse functions and …

Terpenoids, also called isoprenoids, are a large and highly diverse family of natural
products with important medical and industrial properties. However, a limited production of …

Isoprenoids, often called terpenoids, are the most abundant and highly diverse family of
natural organic compounds. In plants, they play a distinct role in the form of photosynthetic …

The fraction of sp3-hybridized carbons (F sp3) and the fraction of stereogenic carbons (F
Cstereo) are two widely employed scores of molecular complexity with strong links to …

Terpenoids are a large class of natural compounds based on the C5 isoprene unit, with
many biological effects such activity against cancer and allergies, while some also have an …

Combining biosynthetic enzymes from multiple pathways is an attractive approach for
producing molecules with desired structural features; however, progress has been …

The strong biological rationale to pursue challenging drug targets such as protein–protein
interactions has stimulated the development of novel screening strategies, such as DNA …