An overview of chronic kidney disease pathophysiology: The impact of gut dysbiosis and oral disease

S Altamura, D Pietropaoli, F Lombardi, R Del Pinto… - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is a severe condition and a significant public health issue
worldwide, carrying the burden of an increased risk of cardiovascular events and mortality …

Gut microbiome, functional food, atherosclerosis, and vascular calcifications—Is there a missing link?

D Cretoiu, RF Ionescu, RM Enache, SM Cretoiu… - Microorganisms, 2021 - mdpi.com
The gut microbiome is represented by the genome of all microorganisms (symbiotic,
potential pathogens, or pathogens) residing in the intestine. These ecological communities …

Biomimetic grapefruit-derived extracellular vesicles for safe and targeted delivery of sodium thiosulfate against vascular calcification

W Feng, Y Teng, Q Zhong, Y Zhang, J Zhang, P Zhao… - ACS …, 2023 - ACS Publications
As the prevalence of vascular calcification (VC), a strong contributor to cardiovascular
morbidity and mortality, continues to increase, the need for pharmacologic therapies …

Relationship between gut microbiota and vascular calcification in hemodialysis patients

WH Bao, WL Yang, CY Su, XH Lu, L He, AH Zhang - Renal Failure, 2023 - Taylor & Francis
Introduction Vascular calcification (VC) is an independent risk factor for cardiovascular
mortality in end-stage renal disease (ESRD) patients. The pathogenesis of VC is …

Vascular calcification and the gut and blood microbiome in chronic kidney disease patients on peritoneal dialysis: a pilot study

A Merino-Ribas, R Araujo, L Pereira, J Campos… - Biomolecules, 2022 - mdpi.com
Vascular calcification (VC) is a frequent condition in chronic kidney disease (CKD) and a
well-established risk factor for the development of cardiovascular disease (CVD). Gut …

Chronic kidney disease mineral bone disorder in childhood and young adulthood: a 'growing'understanding

AD Lalayiannis, EMD Soeiro, RMA Moysés… - Pediatric Nephrology, 2024 - Springer
Chronic kidney disease (CKD) mineral and bone disorder (MBD) comprises a triad of
biochemical abnormalities (of calcium, phosphate, parathyroid hormone and vitamin D) …

Osteoporosis and vascular calcifications

N Martini, L Streckwall, AD McCarthy - Endocrine Connections, 2023 - ec.bioscientifica.com
In post-menopausal women, aged individuals, and patients with diabetes mellitus or chronic
renal disease, bone mineral density (BMD) decreases while the vasculature accumulates …

Novel post-translational modifications in the kidneys for human health and diseases

T Xiang, S Zhao, Y Wu, L Li, P Fu, L Ma - Life Sciences, 2022 - Elsevier
Short-chain fatty acids (SFCAs) exhibit diverse functions from kidneys to human health and
diseases, and also could exert their roles in post-translational modifications (PTMs) …

Relationship between arginine methylation and vascular calcification

C Chen, Y Ding, Q Huang, C Zhang, Z Zhao, H Zhou… - Cellular …, 2024 - Elsevier
In patients on maintenance hemodialysis (MHD), vascular calcification (VC) is an
independent predictor of cardiovascular disease (CVD), which is the primary cause of death …

Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway

QY Hao, J Yan, JT Wei, YH Zeng, LY Feng, DD Que… - Gut …, 2024 - Taylor & Francis
Emerging evidence indicates that alteration of gut microbiota plays an important role in
chronic kidney disease (CKD)-related vascular calcification (VC). We aimed to investigate …