In the last two decades, there has been growing interest in mRNA-based technology for the
development of prophylactic vaccines against infectious diseases. Technological …

The same genetic variant found in different individuals can cause a range of diverse
phenotypes, from no discernible clinical phenotype to severe disease, even among related …

Life implies movement. Most forms of movement in the living world are powered by tiny
protein machines known as molecular motors. Among the best known are motors that use …

Gene expression is finely regulated at the post-transcriptional level. Features of the
untranslated regions of mRNAs that control their translation, degradation and localization …

Although subcellular mRNA trafficking has been demonstrated as a mechanism to control
protein distribution, it is generally believed that most protein localization occurs subsequent …

Extracellular vesicles (EVs) comprise a heterogeneous group of small membrane vesicles,
including exosomes, which play a critical role in intracellular communication and regulation …

Despite intensive studies, the molecular mechanisms by which the genetic materials are
uploaded into microvesicles (MVs) are still unknown. This is the first study describing a …

Recent studies have revealed the operation of a long-distance communication network
operating within the vascular system of higher plants. The evolutionary development of this …

In most cases, translational control mechanisms result from the interaction of RNA-binding
proteins with 5′-or 3′-untranslated regions (UTRs) of mRNA. In organisms ranging from …

Genome Wide Association Studies (GWAS) have mapped thousands of genetic variants
associated with complex disease risk and regulating quantitative traits, thus exploiting an …