Multifaceted design and emerging applications of tissue adhesives

Z Ma, G Bao, J Li - Advanced Materials, 2021 - Wiley Online Library
Tissue adhesives can form appreciable adhesion with tissues and have found clinical use in
a variety of medical settings such as wound closure, surgical sealants, regenerative …

Biomaterials-based regenerative strategies for skin tissue wound healing

G Kaur, G Narayanan, D Garg… - ACS Applied Bio …, 2022 - ACS Publications
Skin tissue wound healing proceeds through four major stages, including hematoma
formation, inflammation, and neo-tissue formation, and culminates with tissue remodeling …

Injectable, self-healing hydrogel adhesives with firm tissue adhesion and on-demand biodegradation for sutureless wound closure

H Ren, Z Zhang, X Cheng, Z Zou, X Chen, C He - Science advances, 2023 - science.org
Tissue adhesives have garnered extensive interest as alternatives and supplements to
sutures, whereas major challenges still remain, including weak tissue adhesion, inadequate …

[HTML][HTML] Preservation of biomaterials and cells by freeze-drying: Change of paradigm

A Merivaara, J Zini, E Koivunotko, S Valkonen… - Journal of Controlled …, 2021 - Elsevier
Freeze-drying is the most widespread method to preserve protein drugs and vaccines in a
dry form facilitating their storage and transportation without the laborious and expensive cold …

Tissue adhesives: From research to clinical translation

A Bal-Ozturk, B Cecen, M Avci-Adali, SN Topkaya… - Nano Today, 2021 - Elsevier
Sutures, staples, clips, and skin closure strips are used as the gold standard to close
wounds after an injury. In spite of being the present standard of care, the utilization of these …

Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

X Yang, W Liu, N Li, M Wang, B Liang, I Ullah… - Biomaterials …, 2017 - pubs.rsc.org
The formation of stable blood clots or hemostasis is essential to prevent major blood loss
and death from excessive bleeding. However, the body's own coagulation process is not …

Bioadhesives for internal medical applications: a review

W Zhu, YJ Chuah, DA Wang - Acta biomaterialia, 2018 - Elsevier
Bioadhesives such as tissue adhesives, hemostatic agents, and tissue sealants have gained
increasing popularity in different areas of clinical operations during the last three decades …

Hemostatic strategies for uncontrolled bleeding: A comprehensive update

A Malik, FU Rehman, KU Shah… - Journal of Biomedical …, 2021 - Wiley Online Library
Uncontrolled bleeding remains the leading cause of morbidity and mortality across the entire
macrocosm. It refers to excessive loss of blood that occurs inside of body, due to …

Engineering tough, injectable, naturally derived, bioadhesive composite hydrogels

M Tavafoghi, A Sheikhi, R Tutar… - Advanced …, 2020 - Wiley Online Library
Engineering mechanically robust bioadhesive hydrogels that can withstand large strains
may open new opportunities for the sutureless sealing of highly stretchable tissues. While …

Hemostatic biomaterials to halt non-compressible hemorrhage

S Jiang, S Liu, S Lau, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Non-compressible hemorrhage is an unmet clinical challenge, which occurs in inaccessible
sites in the body where compression cannot be applied to stop bleeding. Current treatments …