Brain‐derived neurotrophic factor, depression, and physical activity: making the neuroplastic connection

C Phillips - Neural plasticity, 2017 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

BDNF and hippocampal synaptic plasticity

G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …

[HTML][HTML] The role of BDNF on neural plasticity in depression

T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

E Castrén, M Kojima - Neurobiology of disease, 2017 - Elsevier
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …

[HTML][HTML] Neuronal plasticity and neurotrophic factors in drug responses

E Castrén, H Antila - Molecular psychiatry, 2017 - nature.com
Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other
members of the neurotrophin family, are central mediators of the activity-dependent plasticity …

Neurotrophin signalling: novel insights into mechanisms and pathophysiology

M Mitre, A Mariga, MV Chao - Clinical science, 2017 - portlandpress.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …

Schwann cell interactions with axons and microvessels in diabetic neuropathy

NP Gonçalves, CB Vægter, H Andersen… - Nature Reviews …, 2017 - nature.com
The prevalence of diabetes worldwide is at pandemic levels, with the number of patients
increasing by 5% annually. The most common complication of diabetes is peripheral …

[HTML][HTML] Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

TB Sampaio, AS Savall, MEZ Gutierrez… - Neural regeneration …, 2017 - journals.lww.com
Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

[HTML][HTML] proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus

J Yang, LC Harte-Hargrove, CJ Siao, T Marinic… - Cell reports, 2014 - cell.com
Experience-dependent plasticity shapes postnatal development of neural circuits, but the
mechanisms that refine dendritic arbors, remodel spines, and impair synaptic activity are …

[HTML][HTML] Therapeutic potential of neurotrophins for repair after brain injury: a helping hand from biomaterials

J Houlton, N Abumaria, SFR Hinkley… - Frontiers in …, 2019 - frontiersin.org
Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …