Antibiotic resistance in bacterial communities

M Denk-Lobnig, KB Wood - Current opinion in microbiology, 2023 - Elsevier
Bacteria are single-celled organisms, but the survival of microbial communities relies on
complex dynamics at the molecular, cellular, and ecosystem scales. Antibiotic resistance, in …

Zebrafish: an efficient vertebrate model for understanding role of gut microbiota

H Xia, H Chen, X Cheng, M Yin, X Yao, J Ma… - Molecular …, 2022 - Springer
Gut microbiota plays a critical role in the maintenance of host health. As a low-cost and
genetically tractable vertebrate model, zebrafish have been widely used for biological …

A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut

TJ Smith, D Sundarraman, E Melancon, L Desban… - Cell Host & Microbe, 2023 - cell.com
In a healthy gut, microbes are often aggregated with host mucus, yet the molecular basis for
this organization and its impact on intestinal health are unclear. Mucus is a viscous physical …

From Fluctuations and Disorder to Scaling and Control: The Emergence of Resistance in Microbial Communities

J Moran, KB Wood - Annual Review of Condensed Matter …, 2024 - annualreviews.org
Antibiotics are a cornerstone of modern medicine, and antibiotic resistance is a growing
threat to public health. The evolution of resistance is a multiscale process shaped by many …

The Vibrio type VI secretion system induces intestinal macrophage redistribution and enhanced intestinal motility

JS Ngo, P Amitabh, JG Sokoloff, C Trinh, TJ Wiles… - MBio, 2024 - journals.asm.org
Intestinal microbes, whether resident or transient, influence the physiology of their hosts,
altering both the chemical and the physical characteristics of the gut. An example of the latter …

Disaggregation as an interaction mechanism among intestinal bacteria

D Sundarraman, TJ Smith, JVZ Kast, K Guillemin… - Biophysical …, 2022 - cell.com
The gut microbiome contains hundreds of interacting species that together influence host
health and development. The mechanisms by which intestinal microbes can interact …

Bacterial Modulation of Intestinal Motility through Macrophage Redistribution

JS Ngo, P Amitabh, JG Sokoloff, C Trinh, TJ Wiles… - bioRxiv, 2024 - biorxiv.org
Intestinal microbes, whether resident or transient, influence the physiology of their hosts,
altering both the chemical and the physical characteristics of the gut. An example of the latter …

A mucin-regulated adhesin determines the intestinal biogeography and inflammatory character of a bacterial symbiont

TJ Smith, D Sundarraman, E Melancon, L Desban… - bioRxiv, 2022 - biorxiv.org
In a healthy gut, microbes are often aggregated with host mucus, yet the molecular basis for
this organization and its impact on intestinal health are unclear. Mucus is a viscous physical …

Microscale Spatial Dysbiosis in Oral biofilms Associated with Disease

B Grodner, DT Wu, S Hahm, L Takayasu, N Wen… - bioRxiv, 2024 - biorxiv.org
Microbiome dysbiosis has largely been defined using compositional analysis of
metagenomic sequencing data; however, differences in the spatial arrangement of bacteria …

UV-irradiated rotifers for the maintenance of gnotobiotic zebrafish larvae

SM Rosales, PI Bouchard, EM Olmstead… - bioRxiv, 2024 - biorxiv.org
Host-associated microbial communities profoundly impact the health of humans and other
animals. Zebrafish have proven to be a useful model for uncovering mechanisms of host …