Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Allergen immunotherapy in children user's guide

M Alvaro‐Lozano, CA Akdis, M Akdis… - Pediatric allergy and …, 2020 - Wiley Online Library
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Perinatal and early-life nutrition, epigenetics, and allergy

N Acevedo, B Alashkar Alhamwe, L Caraballo, M Ding… - Nutrients, 2021 - mdpi.com
Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

Non‐specific lipid‐transfer proteins: Allergen structure and function, cross‐reactivity, sensitization, and epidemiology

IJ Skypala, R Asero, D Barber, L Cecchi… - Clinical and …, 2021 - Wiley Online Library
Background Discovered and described 40 years ago, non‐specific lipid transfer proteins
(nsLTP) are present in many plant species and play an important role protecting plants from …

Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma

E Crestani, H Harb, LM Charbonnier, J Leirer… - Journal of Allergy and …, 2020 - Elsevier
Background Food allergy (FA) affects an increasing proportion of children for reasons that
remain obscure. Novel disease biomarkers and curative treatment options are strongly …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …

Progress in understanding hypersensitivity reactions to nonsteroidal anti‐inflammatory drugs

I Doña, N Pérez‐Sánchez, I Eguiluz‐Gracia… - Allergy, 2020 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs), the medications most commonly used for
treating pain and inflammation, are the main triggers of drug hypersensitivity reactions. The …

Molecular allergology and its impact in specific allergy diagnosis and therapy

D Barber, A Diaz‐Perales, MM Escribese… - Allergy, 2021 - Wiley Online Library
Progressive knowledge of allergenic structures resulted in a broad availability of allergenic
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …

Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care

H Breiteneder, Z Diamant, T Eiwegger, WJ Fokkens… - Allergy, 2019 - Wiley Online Library
The specialties of allergy and clinical immunology have entered the era of precision
medicine with the stratification of diseases into distinct disease subsets, specific diagnoses …