Dynamic regulation of the filamentous actin (F-actin) cytoskeleton is critical to numerous
physical cellular processes, including cell adhesion, migration and division. Each of these …

This review presents some of our recent results on active polar gels. Active polar gels are
viscoelastic materials formed by polar filaments which are maintained in a non-equilibrium …

A growing body of data supports a view of the actin cytoskeleton of smooth muscle cells as a
dynamic structure that plays an integral role in regulating the development of mechanical …

Current models of eukaryotic chemotaxis propose that directional sensing causes localized
generation of new pseudopods. However, quantitative analysis of pseudopod generation …

Mesenchymal stem cells (MSCs) give origin to the marrow stromal environment that
supports hematopoiesis. These cells present a wide range of differentiation potentials and a …

Eine Polymerisationsreaktion treibt den ersten Mikromotor an, der nicht Teil eines
biologischen Systems ist. Der Motor nutzt einen Grubbs‐Katalysator, der unsymmetrisch an …

Background The leading actin network in motile cells is composed of two compartments, the
lamellipod and the lamellum. Construction of the lamellipod requires a set of conserved …

At the leading edge of a motile cell, actin polymerizes in close apposition to the plasma
membrane. Here we ask how the machinery for force generation at a leading edge is …

Sophisticated molecular genetic, biochemical and biophysical studies have been used to
probe the molecular mechanism of actomyosin-based motility. Recent solution …

Lamellipodia/ruffles and filopodia are protruding organelles containing short and highly
branched or long and unbranched actin filaments, respectively,,. The microscopic …