Recognition of tumors by the innate immune system and natural killer cells

A Marcus, BG Gowen, TW Thompson, A Iannello… - Advances in …, 2014 - Elsevier
In recent years, roles of the immune system in immune surveillance of cancer have been
explored using a variety of approaches. The roles of the adaptive immune system have been …

NK cell recognition

LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
NK CELL RECOGNITION | Annual Reviews Menu Publications AZ Journal Information About
Subscribe Give Personal Register/Sign-in 0 Cart Help Journal Information Author Resource …

Activating and inhibitory receptors of natural killer cells

HJ Pegram, DM Andrews, MJ Smyth… - Immunology and cell …, 2011 - Wiley Online Library
Natural killer (NK) cells are potent immune effector cells that can respond to infection and
cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …

NK cell receptors

LL Lanier - Annual review of immunology, 1998 - annualreviews.org
▪ Abstract NK cells are regulated by opposing signals from receptors that activate and inhibit
effector function. While positive stimulation may be initiated by an array of co-stimulatory …

A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells

M Colonna, F Navarro, T Bellón, M Llano… - The Journal of …, 1997 - rupress.org
Natural killer (NK) cell–mediated lysis is negatively regulated by killer cell inhibitory
receptors specific for major histocompatibility complex (MHC) class I molecules. In this study …

Natural killer cells and cancer

J Wu, LL Lanier - Advances in cancer research, 2003 - books.google.com
Natural killer cells and cancer Page 138 Natural Killer Cells and Cancer Jun Wu1 and Lewis L.
Lanier2 1Shanghai China and Genomics, 2 Department Inc., of and Microbiology Chinese …

Association of DAP12 with activating CD94/NKG2C NK cell receptors

LL Lanier, B Corliss, J Wu, JH Phillips - Immunity, 1998 - cell.com
While the inhibitory NK cell receptors for MHC class I express immunoreceptor tyrosine-
based inhibitory motifs that recruit intracellular tyrosine phosphatases and prevent NK cell …

A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules

D Cosman, N Fanger, L Borges, M Kubin, W Chin… - Immunity, 1997 - cell.com
The human cytomegalovirus UL18 gene product is a homolog of cellular major
histocompatibility (MHC) class I antigens. UL18 has been proposed to protect virus-infected …

[HTML][HTML] LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes

L Meyaard, GJ Adema, C Chang, E Woollatt… - Immunity, 1997 - cell.com
In the present study, we describe a novel inhibitory receptor, leukocyte-associated
immunoglobulin-like receptor-1 (LAIR-1), that is constitutively expressed on the majority of …

NK cell self tolerance, responsiveness and missing self recognition

N Shifrin, DH Raulet, M Ardolino - Seminars in immunology, 2014 - Elsevier
Natural killer (NK) cells represent a first line of defense against pathogens and tumor cells.
The activation of NK cells is regulated by the integration of signals deriving from activating …