Leishmaniasis: complexity at the host–pathogen interface
P Kaye, P Scott - Nature reviews microbiology, 2011 - nature.com
Leishmania is a genus of protozoan parasites that are transmitted by the bite of
phlebotomine sandflies and give rise to a range of diseases (collectively known as …
phlebotomine sandflies and give rise to a range of diseases (collectively known as …
[HTML][HTML] Roles of oxidative stress and Nrf2 signaling in pathogenic and non-pathogenic cells: a possible general mechanism of resistance to therapy
M Hammad, M Raftari, R Cesário, R Salma, P Godoy… - Antioxidants, 2023 - mdpi.com
The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …
[HTML][HTML] Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid
JY Lee, W Park - Molecules, 2011 - mdpi.com
Myristicin (1-allyl-5-methoxy-3, 4-methylenedioxybenzene) is an active aromatic compound
found in nutmeg (the seed of Myristica fragrans), carrot, basil, cinnamon, and parsley …
found in nutmeg (the seed of Myristica fragrans), carrot, basil, cinnamon, and parsley …
Toll‐Like Receptors in Leishmania Infections: Guardians or Promoters?
MS Faria, FCG Reis, APCA Lima - Journal of parasitology …, 2012 - Wiley Online Library
Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …
Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis
M Rossi, P Castiglioni, MA Hartley… - Proceedings of the …, 2017 - National Acad Sciences
The presence of the endogenous Leishmania RNA virus 1 (LRV1) replicating stably within
some parasite species has been associated with the development of more severe forms of …
some parasite species has been associated with the development of more severe forms of …
Emerging therapeutic targets for treatment of leishmaniasis
S Sundar, B Singh - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …
Glycoconjugates in New World species of Leishmania: polymorphisms in lipophosphoglycan and glycoinositolphospholipids and interaction with hosts
RR de Assis, IC Ibraim, PM Nogueira… - … et Biophysica Acta (BBA …, 2012 - Elsevier
BACKGROUND: Protozoan parasites of the genus Leishmania cause a number of important
diseases in humans and undergo a complex life cycle, alternating between a sand fly vector …
diseases in humans and undergo a complex life cycle, alternating between a sand fly vector …
Interfering with immunity: detrimental role of type I IFNs during infection
SA Stifter, CG Feng - The Journal of Immunology, 2015 - journals.aai.org
Type I IFNs are known to inhibit viral replication and mediate protection against viral
infection. However, recent studies revealed that these cytokines play a broader and more …
infection. However, recent studies revealed that these cytokines play a broader and more …
Genome-wide detection of natural selection in African Americans pre-and post-admixture
It is particularly meaningful to investigate natural selection in African Americans (AfA) due to
the high mortality their African ancestry has experienced in history. In this study, we …
the high mortality their African ancestry has experienced in history. In this study, we …
[HTML][HTML] Function of macrophage and parasite phosphatases in leishmaniasis
The kinetoplastid protozoan parasites belonging to the genus Leishmania are the causative
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …