The current view of diabetic kidney disease, based on meticulously acquired ultrastructural
morphometry and the utility of measuring plasma creatinine and urinary albumin, has been …

Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high
morbidity and mortality rates. The development of novel therapies for sepsis is critically …

This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological …

Diabetes mellitus is a severe metabolic disorder, which consistently requires medical care
and self-management to restrict complications, such as obesity, kidney damage and …

Endothelial dysfunction is regarded as an important factor in the pathogenesis of vascular
disease in obesity‐related type 2 diabetes. The imbalance in repair and injury …

Diabetic cardiomyopathy is related directly to hyperglycemia. Cell death such as apoptosis
plays a critical role in cardiac pathogenesis. Whether hyperglycemia induces myocardial …

To reconstruct the mechanisms for the vasoobliteration that transforms diabetic retinopathy
into an ischemic retinopathy, we compared the occurrence of cell death in situ in retinal …

The endothelium is a complex organ with a multitude of properties essential for control of
vascular functions. Dysfunction of the vascular endothelium is regarded as an important …

Background—Diabetes mellitus impairs endothelial cell (EC) function and postischemic
reparative neovascularization by molecular mechanisms that are not fully understood …

Objectives: We sought to establish whether a reduction in endothelial progenitor cells
(EPCs) has a putative role in peripheral vascular disease (PVD) of type 2 diabetic patients …