Polyunsaturated fatty acids (PUFAs) and their metabolites have a variety of physiological
roles including: energy provision, membrane structure, cell signaling and regulation of gene …

Biologically active environmental pollutants have significant impact on ecosystems, wildlife,
and human health. Microplastic (MP) and nanoplastic (NP) particles are pollutants that are …

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine
and drug development, having made inestimable contributions to human health. We report …

When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

The first edition of Bioanalytical Tools in Water Quality Assessment was released in 2012.
The field has exploded since and the second edition updates and reviews the application of …

Nuclear receptors (NRs) are ligand-activated transcription factors sharing a common
evolutionary history and having similar sequence features at the protein level. Selective …

Nuclear receptors are intracellular proteins that act as transcription factors. Proteins with
classic nuclear receptor domain structure lacking identified signaling ligands are designated …

Characterization and biological roles of the peroxisome proliferator‐activated receptor
(PPAR) isotypes are well known in monogastrics, but not in ruminants. However, a wealth of …

Bilaterian animals are notably characterized by complex endocrine systems. The receptors
for many steroids, retinoids, and other hormones belong to the superfamily of nuclear …

Transcription factors with aberrant activity in disease are promising yet untested targets for
therapeutic development, particularly in oncology. Directly inhibiting or activating the …