Genotoxicity induced by hexavalent chromium leading to eryptosis in Ctenopharyngodon idellus
K Handa, R Jindal - Chemosphere, 2020 - Elsevier
The initiation of eryptosis as a result of genotoxic action of Cr (VI), seen through
micronucleus and comet assay in the peripheral erythrocytes of Ctenopharyngodon idellus …
micronucleus and comet assay in the peripheral erythrocytes of Ctenopharyngodon idellus …
Assessment of the Genotoxic Potential of Azidothymidine in the Comet, Micronucleus, and Pig-a Assay
The genotoxic potential of azidothymidine (Zidovudine, AZT), chosen as a model compound
for nucleotide analogs, was comprehensively assessed in vivo for gene mutation …
for nucleotide analogs, was comprehensively assessed in vivo for gene mutation …
Influence of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, in the evaluation of the genotoxicity of doxorubicin, cyclophosphamide and zidovudine …
Testing new chemical entities for genotoxicity is an integral part of the preclinical drug-
development process. Lowering the detection limit and enhancing the sensitivity of …
development process. Lowering the detection limit and enhancing the sensitivity of …
Pretreatment with valproic acid, a histone deacetylase inhibitor, enhances the sensitivity of the peripheral blood micronucleus assay in rodents
Micronucleus (MN) assay is widely used for the determination of the genotoxic potential of
new chemical entities. Improvement in the sensitivity of MN assay will be advantageous for …
new chemical entities. Improvement in the sensitivity of MN assay will be advantageous for …
3-Aminobenzamide–a PARP inhibitor enhances the sensitivity of peripheral blood micronucleus and comet assays in mice
Context: DNA repair is an essential outcome of DNA damage, which may compromise the
end point of various in vitro and in vivo test systems of the genotoxicity evaluation. poly (ADP …
end point of various in vitro and in vivo test systems of the genotoxicity evaluation. poly (ADP …
Does bleeding induce micronuclei via erythropoietin in Han-Wistar rats?
J Molloy, JR Foster, H Thomas… - Toxicology …, 2014 - academic.oup.com
The effects of both intravenous administration of recombinant human erythropoietin (rhEPO)
and blood withdrawal, either individually or in combination, on the frequency of …
and blood withdrawal, either individually or in combination, on the frequency of …