Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Most of the biomedical materials printed using 3D bioprinting are static and are unable to
alter/transform with dynamic changes in the internal environment of the body. The …

Recent years have seen much excitement over the possibility that adult mammalian stem
cells may be capable of differentiating across tissue lineage boundaries, and as such may …

Mesenchymal stem cells are multipotent cells that can differentiate into cardiomyocytes and
vascular endothelial cells. Here we show, using cell sheet technology, that monolayered …

As part of the TACTICS (Transnational Alliance for Regenerative Therapies in
Cardiovascular Syndromes) series to enhance regenerative medicine, here, we discuss the …

Repair of the heart is an old dream of physicians caring for patients with cardiac disease.
Experimental studies suggest that cardiac transfer of stem and progenitor cells can have a …

Acute myocardial infarction and chronic heart failure rank among the major causes of
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …

The aim of the study was to investigate whether a combination of mesenchymal stem cells
(MSCs) capable of differentiating into cardiac myocytes and endothelial progenitors (EPCs) …

Aims Stem cell therapy is a treatment strategy for ischaemic heart disease patients. Meta-
analysis of randomized human trials showed< 5% improvement in left ventricular ejection …

Background Heart failure develops after myocardial infarction and is a major cause of
morbidity and mortality. The ability to direct differentiation of embryonic stem cells (ESC) …