Apoptosis, as a very important biological process, is a response to developmental cues or
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …

Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer-
related death worldwide. The treatment of HCC remains challenging and is largely …

Background Alveolar soft part sarcoma (ASPS) is a rare soft-tissue sarcoma with a poor
prognosis and no established therapy. Recently, encouraging responses to immune …

Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

The last 3 years have seen the emergence of promising targeted therapies for the treatment
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …

Ferroptosis is a recently discovered form of programed cell death caused by the
metabolically regulated lipid peroxidation and holds promise for cancer treatment, but its …

Tumor‐associated macrophages (TAMs) play an essential role in tumor progression,
metastasis, and antitumor immunity. Ferroptosis has attracted extensive attention for its …

Heterogeneity is the major challenge for cancer prevention and therapy. Here, we first
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …

Ferroptosis is a new type of cell death that has been recognized in recent years and is
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …

With advances in sequencing and instrument technology, bioinformatics analysis is being
applied to batches of massive cells at single-cell resolution. High-throughput single-cell …