Prevention of vascular contributions to cognitive impairment and dementia: the role of physical activity and exercise
Vascular contributions to cognitive impairment and dementia, specifically cerebral small
vessel disease (CSVD), are the second most common cause of dementia. Currently, there …
vessel disease (CSVD), are the second most common cause of dementia. Currently, there …
Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank
Y Zhang, SD Chen, YT Deng, J You, XY He… - Nature human …, 2023 - nature.com
Previous hypothesis-driven research has identified many risk factors linked to dementia.
However, the multiplicity and co-occurrence of risk factors have been underestimated. Here …
However, the multiplicity and co-occurrence of risk factors have been underestimated. Here …
Grip strength is inversely associated with DNA methylation age acceleration
MD Peterson, S Collins, HCS Meier… - Journal of cachexia …, 2023 - Wiley Online Library
Background There is a large body of evidence linking muscular weakness, as determined by
low grip strength, to a host of negative ageing‐related health outcomes. Given these links …
low grip strength, to a host of negative ageing‐related health outcomes. Given these links …
[HTML][HTML] Different resistance exercise interventions for handgrip strength in apparently healthy adults: A systematic review
Background: Although handgrip strength is a biomarker for morbidity/mor-tality, there is lack
of evidence on the effects of resistance training on handgrip strength in healthy adults of all …
of evidence on the effects of resistance training on handgrip strength in healthy adults of all …
Bridging Reduced Grip Strength and Altered Executive Function: Specific Brain White Matter Structural Changes in Patients with Alzheimer's Disease
SW Liu, XT Ma, S Yu, XF Weng, M Li, J Zhu… - … Interventions in Aging, 2024 - Taylor & Francis
Objective To investigate the correlation between specific fiber tracts and grip strength and
cognitive function in patients with Alzheimer's disease (AD) by fixel-based analysis (FBA) …
cognitive function in patients with Alzheimer's disease (AD) by fixel-based analysis (FBA) …
Walking pace, handgrip strength, age, APOE genotypes, and new-onset dementia: the UK Biobank prospective cohort study
P He, C Zhou, Z Ye, M Liu, Y Zhang, Q Wu… - Alzheimer's research & …, 2023 - Springer
Background The independent and additive associations of walking pace and grip strength
on dementia risk and the potential modifying effects of age, APOE phenotypes, and other …
on dementia risk and the potential modifying effects of age, APOE phenotypes, and other …
Peripheral GFAP and NfL as early biomarkers for dementia: longitudinal insights from the UK Biobank
X Wang, Z Shi, Y Qiu, D Sun, H Zhou - BMC medicine, 2024 - Springer
Background Peripheral glial fibrillary acidic protein (GFAP) and neurofilament light chain
(NfL) are sensitive markers of neuroinflammation and neuronal damage. Previous studies …
(NfL) are sensitive markers of neuroinflammation and neuronal damage. Previous studies …
[HTML][HTML] Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach
JL Centa, MP Stratton, MA Pratt, JRO Oltmanns… - … Therapy-Nucleic Acids, 2023 - cell.com
Genetic mutations that disrupt open reading frames and cause translation termination are
frequent causes of human disease and are difficult to treat due to protein truncation and …
frequent causes of human disease and are difficult to treat due to protein truncation and …
The relationship between sarcopenia, cognitive impairment, and cerebral white matter hyperintensity in the elderly
K Zhang, K Zhang, Q Liu, J Wu - Clinical Interventions in Aging, 2023 - Taylor & Francis
Purpose To explore the relationship between sarcopenia-related indices, cognitive
impairment and cerebral white matter hyperintensities. Patients and methods Ninety-five …
impairment and cerebral white matter hyperintensities. Patients and methods Ninety-five …
Impaired muscle function, including its decline, is related to greater long‐term late‐life dementia risk in older women
S Radavelli‐Bagatini, H Macpherson… - Journal of Cachexia …, 2023 - Wiley Online Library
Background Impaired muscle function has been identified as a risk factor for declining
cognitive function and cardiovascular health, both of which are risk factors for late‐life …
cognitive function and cardiovascular health, both of which are risk factors for late‐life …