MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

A period of oocyte growth is followed by a process called oocyte maturation (the resumption
of meiosis) which occurs prior to ovulation and is a prerequisite for successful fertilization …

MicroRNAs (miRNAs) comprise 1 to 3% of all vertebrate genes, but their in vivo functions
and mechanisms of action remain largely unknown. Zebrafish miR-430 is expressed at the …

Fertilization triggers a complex cellular programme that transforms two highly specialized
meiotic germ cells, the oocyte and the sperm, into a totipotent mitotic embryo. Linkages …

Nearly two decades ago, Xenopus oocytes were found to contain mRNAs harboring a small
sequence in their 3′ untranslated regions that control cytoplasmic polyadenylation and …

Oocytes and sperm are some of the most differentiated cells in our bodies, yet they generate
all cell types after fertilization. Accumulating evidence suggests that this extraordinary …

Oocytes, the female germ cells, contain all the messenger RNAs necessary to start a new life
but typically wait until fertilization to begin development. The transition from oocyte to …

The transition from mature oocyte to developing embryo requires a coordinated series of
events, collectively known as egg activation. Egg activation includes changes to egg …

MicroRNAs (miRNAs) are genes involved in normal development and cancer. They inhibit
gene expression by associating with 3'-Untranslated regions (3'UTRs) of messenger RNAs …

In animals, the maternal-to-embryonic transition (MET) occurs in the first days of early
development and involves the degradation of maternal transcripts that have been stored …