[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

[HTML][HTML] Viscoelastic testing and coagulopathy of traumatic brain injury

JL Bradbury, SG Thomas, NR Sorg, N Mjaess… - Journal of clinical …, 2021 - mdpi.com
A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

Coagulopathy and progression of intracranial hemorrhage in traumatic brain injury: mechanisms, impact, and therapeutic considerations

M Maegele - Neurosurgery, 2021 - journals.lww.com
BACKGROUND Traumatic brain injury (TBI) remains one of the most challenging health and
socioeconomic problems of our times. Clinical courses may be complicated by hemostatic …

A metabolomic and proteomic analysis of pathologic hypercoagulability in traumatic brain injury patients after dura violation

JR Coleman, A D'Alessandro, I LaCroix… - Journal of Trauma …, 2023 - journals.lww.com
BACKGROUND The coagulopathy of traumatic brain injury (TBI) remains poorly understood.
Contradictory descriptions highlight the distinction between systemic and local coagulation …

[HTML][HTML] Acute Haemostatic Depletion and Failure in Patients with Traumatic Brain Injury (TBI): Pathophysiological and Clinical Considerations

F Kockelmann, M Maegele - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Because of the aging population, the number of low falls in elderly people with
pre-existing anticoagulation is rising, often leading to traumatic brain injury (TBI) with a …

Neutrophil to lymphocyte ratio in the prediction of coagulopathy in traumatic brain injury

GA Alexiou, A Tzima, GD Lianos, M Lampros… - Biomarkers in …, 2022 - Future Medicine
Aim: Traumatic brain injury (TBI) is a public health issue of increasing incidence.
Coagulopathy after TBI is a frequent event, associated with a poor prognosis, and …

Coagulopathy in isolated traumatic brain injury: myth or reality

R Mathur, JI Suarez - Neurocritical care, 2023 - Springer
Abstract Introduction Traumatic Brain Injury (TBI) has been shown to be associated with
altered hemostasis and coagulopathy, that correlates with worsening secondary injury and …

Association of extravascular leakage on computed tomography angiography with fibrinogen levels at admission in patients with traumatic brain injury

H Ito, Y Nakamura, Y Togami, S Onishi… - Neurotrauma …, 2023 - liebertpub.com
Extravascular leakage on computed tomography (CT) angiography in patients with traumatic
brain injury (TBI) is associated with hematoma expansion, functional prognosis, subsequent …

Efficacy and safety of fibrinogen administration in acute post-traumatic hypofibrinogenemia in isolated severe traumatic brain injury: A randomized clinical trial

M Sabouri, M Vahidian, A Sourani, SB Mahdavi… - Journal of Clinical …, 2022 - Elsevier
Aim This study was conducted to evaluate clinical outcomes after fibrinogen administration
in hypofibrinogenemia following severe traumatic brain injury. Background Post traumatic …

Controversies and evidence gaps in the early management of severe traumatic brain injury: back to the ABCs

ST El-Swaify, MA Refaat, SH Ali… - Trauma Surgery & …, 2022 - tsaco.bmj.com
Traumatic brain injury (TBI) accounts for around 30% of all trauma-related deaths. Over the
past 40 years, TBI has remained a major cause of mortality after trauma. The primary injury …