CREBH regulates systemic glucose and lipid metabolism
Y Nakagawa, H Shimano - International journal of molecular sciences, 2018 - mdpi.com
The cyclic adenosine monophosphate (cAMP)-responsive element-binding protein H
(CREBH, encoded by CREB3L3) is a membrane-bound transcriptional factor that primarily …
(CREBH, encoded by CREB3L3) is a membrane-bound transcriptional factor that primarily …
The transcription factors CREBH, PPARa, and FOXO1 as critical hepatic mediators of diet-induced metabolic dysregulation
The liver is a critical mediator of lipid and/or glucose homeostasis and is a primary organ
involved in dynamic changes during feeding and fasting. Additionally, hepatic-centric …
involved in dynamic changes during feeding and fasting. Additionally, hepatic-centric …
Target deconvolution of fenofibrate in nonalcoholic fatty liver disease using bioinformatics analysis
A Mahmoudi, AE Butler… - BioMed research …, 2021 - Wiley Online Library
Background. Nonalcoholic fatty liver disease (NAFLD) is a prevalent form of liver damage,
affecting~ 25% of the global population. NAFLD comprises a spectrum of liver pathologies …
affecting~ 25% of the global population. NAFLD comprises a spectrum of liver pathologies …
Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα
Abstract Background Peroxisome Proliferator-Activated receptor α (PPARα) and cAMP-
Responsive Element Binding Protein 3-Like 3 (CREB3L3) are transcription factors involved …
Responsive Element Binding Protein 3-Like 3 (CREB3L3) are transcription factors involved …
The role and mechanism of CREBH regulating SIRT3 in metabolic associated fatty liver disease
Z Junli, W Shuhan, Z Yajuan, D Xiaoling, L Jiahuan… - Life Sciences, 2022 - Elsevier
Aims To investigate the effect of cAMP response element-binding protein H (CREBH) on
metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3). Main methods Two …
metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3). Main methods Two …
[HTML][HTML] Enterohepatic transcription factor CREB3L3 protects atherosclerosis via SREBP competitive inhibition
Y Nakagawa, Y Wang, S Han, K Okuda, A Oishi… - Cellular and Molecular …, 2021 - Elsevier
Background & Aims cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a
membrane-bound transcription factor involved in the maintenance of lipid metabolism in the …
membrane-bound transcription factor involved in the maintenance of lipid metabolism in the …
Transcriptional regulation of fibroblast growth factor 21 expression
KH Bae, JG Kim, KG Park - Endocrinology and metabolism, 2014 - synapse.koreamed.org
Fibroblast growth factor 21 (FGF21) is an attractive target for treating metabolic disease due
to its wide-ranging beneficial effects on glucose and lipid metabolism. Circulating FGF21 …
to its wide-ranging beneficial effects on glucose and lipid metabolism. Circulating FGF21 …
[HTML][HTML] Pluchea indica leaf extract alleviates dyslipidemia and hepatic steatosis by modifying the expression of lipid metabolism-related genes in rats fed a high fat …
P Singdam, J Naowaboot, L Senggunprai… - … Nutrition and Food …, 2022 - ncbi.nlm.nih.gov
This study evaluated the effect of Pluchea indica leaf extract (PIE) on dyslipidemia and lipid
accumulation in the liver, emphasizing its molecular mechanisms in regulating lipid …
accumulation in the liver, emphasizing its molecular mechanisms in regulating lipid …
[HTML][HTML] Disrupted Microbiota of Colon Results in Worse Immunity and Metabolism in Low-Birth-Weight Jinhua Newborn Piglets
J Li, Z Wei, F Lou, X Zhang, J Duan, C Luo, X Hu, P Tu… - Microorganisms, 2024 - mdpi.com
The Jinhua pig is well known in China due to its delicious meat. However, because of large
litter size, low birth weight always happens. This experiment used this breed as a model to …
litter size, low birth weight always happens. This experiment used this breed as a model to …
Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression
AK Min, KH Bae, YA Jung, YK Choi, MJ Kim… - …, 2014 - academic.oup.com
The fasting-induced hepatic hormone, fibroblast growth factor 21 (FGF21), is a potential
candidate for the treatment of metabolic syndromes. Although peroxisome proliferator …
candidate for the treatment of metabolic syndromes. Although peroxisome proliferator …