Progression of motor symptoms in Parkinson's disease

R Xia, ZH Mao - Neuroscience bulletin, 2012 - Springer
Parkinson's disease (PD) is a chronic progressive neurodegenerative disease that is
clinically manifested by a triad of cardinal motor symptoms—rigidity, bradykinesia and …

[HTML][HTML] Wrist rigidity evaluation in Parkinson's disease: a scoping review

CM Alves, AR Rezende, IA Marques, LC Mendes… - Healthcare, 2022 - mdpi.com
(1) Background: One of the main cardinal signs of Parkinson's disease (PD) is rigidity,
whose assessment is important for monitoring the patient's recovery. The wrist is one of the …

Axial hypertonicity in Parkinson's disease: direct measurements of trunk and hip torque

WG Wright, VS Gurfinkel, J Nutt, FB Horak… - Experimental …, 2007 - Elsevier
A cardinal feature of Parkinson's disease (PD) is muscle hypertonicity, ie rigidity. Little is
known about the axial tone in PD or the relation of hypertonia to functional impairment. We …

PDMeter: A wrist wearable device for an at-home assessment of the Parkinson's disease rigidity

L Raiano, G di Pino, L di Biase… - … on Neural Systems …, 2020 - ieeexplore.ieee.org
This work focuses on the design and the validation of a wearable mechatronic device for an
at-home assessment of wrist stiffness in patients affected by Parkinson's Disease (PD). The …

Stretch reflex spatial threshold measure discriminates between spasticity and rigidity

AA Mullick, NK Musampa, AG Feldman… - Clinical …, 2013 - Elsevier
OBJECTIVE: Muscle spasticity following stroke has been shown to result from limitations in
the range of regulation of the tonic reflex spatial threshold (ST), ie, the joint angle at which …

A novel method for systematic analysis of rigidity in Parkinson's disease

T Endo, R Okuno, M Yokoe, K Akazawa… - … : official journal of the …, 2009 - Wiley Online Library
We propose a novel system that analyzes the components of rigidity in Parkinson's disease
(PD) usually perceived by physicians, in a very simple and systematic way for routine clinical …

Objective measurement of muscle rigidity in Parkinsonian patients treated with subthalamic stimulation

J Levin, S Krafczyk, P Valkovič, T Eggert… - Movement …, 2009 - Wiley Online Library
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been shown to be an
effective treatment for Parkinson's disease (PD). The intraoperative positioning of DBS …

Effects of STN DBS on rigidity in Parkinson's disease

MB Shapiro, DE Vaillancourt… - … on Neural Systems …, 2007 - ieeexplore.ieee.org
We quantified the effects of deep brain stimulation (DBS) of the subthalamic nucleus (STN)
and medication on Parkinsonian rigidity using an objective measure of work about the elbow …

REM sleep without atonia is associated with increased rigidity in patients with mild to moderate Parkinson's disease

ME Linn-Evans, MN Petrucci, SLA Huffmaster… - Clinical …, 2020 - Elsevier
Objective Increased muscle activity during rapid eye movement (REM) sleep (ie REM sleep
without atonia) is common in people with Parkinson's disease (PD). This study tested the …

Analysis of viscoelastic properties of wrist joint for quantification of parkinsonian rigidity

BK Park, Y Kwon, JW Kim, JH Lee… - … on Neural Systems …, 2010 - ieeexplore.ieee.org
This study aims to analyze viscoelastic properties of the wrist in patients with Parkinson's
disease (PD) in comparison with the clinical score of severity. Forty-five patients with PD and …