A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

A conduit to metastasis: circulating tumor cell biology

DS Micalizzi, S Maheswaran… - Genes & …, 2017 - genesdev.cshlp.org
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for
detection and characterization of circulating tumor cells (CTCs) from patients with cancer …

Technologies for circulating tumor cell separation from whole blood

P Bankó, SY Lee, V Nagygyörgy, M Zrínyi… - Journal of hematology & …, 2019 - Springer
The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

[HTML][HTML] Challenges in circulating tumor cell detection by the CellSearch system

KC Andree, G van Dalum, LWMM Terstappen - Molecular oncology, 2016 - Elsevier
Enumeration and characterization of circulating tumor cells (CTC) hold the promise of a real
time liquid biopsy. They are however present in a large background of hematopoietic cells …

Vasculogenic mimicry in small cell lung cancer

SC Williamson, RL Metcalf, F Trapani, S Mohan… - Nature …, 2016 - nature.com
Small cell lung cancer (SCLC) is characterized by prevalent circulating tumour cells (CTCs),
early metastasis and poor prognosis. We show that SCLC patients (37/38) have rare CTC …

Determination of PD-L1 expression in circulating tumor cells of NSCLC patients and correlation with response to PD-1/PD-L1 inhibitors

M Janning, F Kobus, A Babayan, H Wikman… - Cancers, 2019 - mdpi.com
Circulating tumor cells (CTCs) hold great potential to answer key questions of how non-
small cell lung cancer (NSCLC) evolves and develops resistance upon anti-PD-1/PD-L1 …

CTC clusters in cancer progression and metastasis

A Fabisiewicz, E Grzybowska - Medical Oncology, 2017 - Springer
Circulating tumor cells (CTC) in the blood of cancer patients are regarded as potential
metastatic seeds, and their detailed characterization holds great promises for more exact …

Orchestration of collective migration and metastasis by tumor cell clusters

A Yamamoto, AE Doak… - Annual Review of …, 2023 - annualreviews.org
Metastatic dissemination has lethal consequences for cancer patients. Accruing evidence
supports the hypothesis that tumor cells can migrate and metastasize as clusters of cells …

Circulating tumor cells in diagnosis and treatment of lung cancer

V Maly, O Maly, K Kolostova, V Bobek - in vivo, 2019 - iv.iiarjournals.org
Circulating tumor cells (CTCs), detached from the primary tumor or metastases and shed in
the patient's bloodstream, represent a relatively easily obtainable sample of the cancer …

Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications

R Harouaka, Z Kang, SY Zheng, L Cao - Pharmacology & therapeutics, 2014 - Elsevier
Circulating tumor cells (CTCs) are rare cancer cells released from tumors into the
bloodstream that are thought to have a key role in cancer metastasis. The presence of CTCs …