Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Candida albicans cell-type switching and functional plasticity in the mammalian host

SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …

Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review

N Kalia, J Singh, M Kaur - Annals of clinical microbiology and …, 2020 - Springer
Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and
clinical problem but also include large social and psychological consequences …

Recurrent vulvovaginal candidiasis: an immunological perspective

D Rosati, M Bruno, M Jaeger, J Ten Oever, MG Netea - Microorganisms, 2020 - mdpi.com
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by
Candida albicans. VVC affects up to 75% of women of childbearing age once in their life …

Vulvovaginal Candida albicans infections: pathogenesis, immunity and vaccine prospects

A Cassone - BJOG: An International Journal of Obstetrics & …, 2015 - Wiley Online Library
Although a number of fungal species belonging to the genus C andida can cause acute
vulvovaginal infection (VVC), C andida albicans is by far the most prevalent etiological …

An Update on the Roles of Non-albicans Candida Species in Vulvovaginitis

O Makanjuola, F Bongomin, SA Fayemiwo - Journal of Fungi, 2018 - mdpi.com
Candida species are one of the commonest causes of vaginitis in healthy women of
reproductive age. Vulvovaginal candidiasis (VVC) is characterized by vulvovaginal itching …

Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa

JP Richardson, HME Willems, DL Moyes… - Infection and …, 2018 - Am Soc Microbiol
Unlike other forms of candidiasis, vulvovaginal candidiasis, caused primarily by the fungal
pathogen Candida albicans, is a disease of immunocompetent and otherwise healthy …

The vaginal mycobiome: A contemporary perspective on fungi in women's health and diseases

LL Bradford, J Ravel - Virulence, 2017 - Taylor & Francis
Most of what is known about fungi in the human vagina has come from culture-based studies
and phenotypic characterization of single organisms. Though valuable, these approaches …

Anticandidal activity of biosynthesized silver nanoparticles: effect on growth, cell morphology, and key virulence attributes of Candida species

M Jalal, MA Ansari, MA Alzohairy, SG Ali… - International journal …, 2019 - Taylor & Francis
Purpose: The pathogenicity in Candida spp was attributed by several virulence factors such
as production of tissue damaging extracellular enzymes, germ tube formation, hyphal …

Neutrophil swarming delays the growth of clusters of pathogenic fungi

A Hopke, A Scherer, S Kreuzburg, MS Abers… - Nature …, 2020 - nature.com
Neutrophils employ several mechanisms to restrict fungi, including the action of enzymes
such as myeloperoxidase (MPO) or NADPH oxidase, and the release of neutrophil …