The authors of this review both served on the National Academy of Science, Engineering,
and Medicine Committee that produced the report,“Social Isolation and Loneliness in Older …

The review synthesised evidence examining the association between a. loneliness with
inflammation and b. social isolation with inflammation in adults aged 16 or older from the …

Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

There is growing evidence that loneliness is associated with mild cognitive impairment (MCI)
and dementia. However, the extent of this association remains unclear. A systematic review …

Loneliness has been defined as an agonizing encounter, experienced when the need for
human intimacy is not met adequately, or when a person's social network does not match …

Older adults are at an increased risk of loneliness. Many also serve as informal caregivers
for persons with dementia and other disabling conditions, further predisposing them to …

Background Despite the well-known health benefits of physical activity (PA), older adults are
the least active citizens. Older adults are also at risk for loneliness. Given that lonely …

Objective Several psychosocial risk factors have been identified that increase the rate of
readmission in heart failure (HF) patients. However, the impact of social isolation (SI) on the …

Objectives This study aimed to explore time-varying associations between social
engagement, living status and loneliness and neuro-immune markers in older adults, and …

Pain and loneliness are consistently associated, but the direction of the relationship is
uncertain. We assessed bidirectional associations over a 4-year period in a sample of 4906 …