Staying in shape: the impact of cell shape on bacterial survival in diverse environments

DC Yang, KM Blair, NR Salama - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria display an abundance of cellular forms and can change shape during their life
cycle. Many plausible models regarding the functional significance of cell morphology have …

Bacterial programmed cell death: making sense of a paradox

KW Bayles - Nature Reviews Microbiology, 2014 - nature.com
Although the concept of programmed cell death (PCD) in bacteria has been met with
scepticism, a growing body of evidence suggests that it can no longer be ignored. Several …

[HTML][HTML] Self-activating anti-infection implant

J Fu, W Zhu, X Liu, C Liang, Y Zheng, Z Li… - Nature …, 2021 - nature.com
Clinically, it is difficult to endow implants with excellent osteogenic ability and antibacterial
activity simultaneously. Herein, the self-activating implants modified with hydroxyapatite …

Post-stress bacterial cell death mediated by reactive oxygen species

Y Hong, J Zeng, X Wang, K Drlica… - Proceedings of the …, 2019 - National Acad Sciences
Antimicrobial efficacy, which is central to many aspects of medicine, is being rapidly eroded
by bacterial resistance. Since new resistance can be induced by antimicrobial action, highly …

The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

Z Cao, MG Casabona, H Kneuper, JD Chalmers… - Nature …, 2016 - nature.com
The type VII protein secretion system (T7SS) plays a critical role in the virulence of human
pathogens including Mycobacterium tuberculosis and Staphylococcus aureus. Here, we …

DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks

KN Kreuzer - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
Recent advances in the area of bacterial DNA damage responses are reviewed here. The
SOS pathway is still the major paradigm of bacterial DNA damage response, and recent …

Emergence of antibiotic resistance from multinucleated bacterial filaments

J Bos, Q Zhang, S Vyawahare… - Proceedings of the …, 2015 - National Acad Sciences
Bacteria can rapidly evolve resistance to antibiotics via the SOS response, a state of high-
activity DNA repair and mutagenesis. We explore here the first steps of this evolution in the …

A novel mechanism for the antibacterial effect of silver nanoparticles on Escherichia coli

W Lee, KJ Kim, DG Lee - Biometals, 2014 - Springer
Silver nanoparticles are known to have antimicrobial properties and have been used
extensively in medicine, although the mechanism (s) of action have not yet been clearly …

Apoptosis-like death, an extreme SOS response in Escherichia coli

A Erental, Z Kalderon, A Saada, Y Smith… - MBio, 2014 - Am Soc Microbiol
In bacteria, SOS is a global response to DNA damage, mediated by the recA-lexA genes,
resulting in cell cycle arrest, DNA repair, and mutagenesis. Previously, we reported that …

[HTML][HTML] A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus

JW Modell, TK Kambara, BS Perchuk, MT Laub - PLoS biology, 2014 - journals.plos.org
Cells must coordinate DNA replication with cell division, especially during episodes of DNA
damage. The paradigm for cell division control following DNA damage in bacteria involves …