Signaling pathways are responsible for transmitting information between cells and
regulating cell growth, differentiation, and death. Proteins in cells form complexes by …

Alzheimer's disease (AD) is the most common cause of dementia worldwide that has an
increasing impact on aging societies. Besides its critical role in the control of various …

Background Homo-and heteromerization of G protein-coupled receptors (GPCRs) plays an
important role in the regulation of receptor functions. Recently, we demonstrated an …

Exposure to organic solvents is associated with various health problems, including
neurodegenerative diseases. Among these solvents, 1, 2-diethylbenzene is notable for its …

Cannabinoids and the endocannabinoid system (ECS) have been intensively studied for
their neuroregulatory roles in the central nervous system (CNS), especially in regulating …

Background Multiple neurodegenerative diseases are induced by the formation and
deposition of protein aggregates. In particular, the microtubule-associated protein Tau leads …

Abstract Changes in brain mitochondrial metabolism are coincident with functional decline;
however, direct links between the two have not been established. Here, we show that …

Serotonin 5-HT7 receptors (5-HT7R) are attracting increasing attention as important
participants in the mechanisms of Alzheimer's disease and as a possible target for the …

The present therapies targeting the Tau proteins prevent the post-translational alterations in
Tau, prevent its accumulation in neurons, prevent destabilization of microtubules, and the …

Аннотация Серотониновые рецепторы 5-HT7 (5-HT7R) привлекают все больше
внимания в качестве одного из важных звеньев в механизмах развития болезни …