Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human

N Gillet, A Florins, M Boxus, C Burteau, A Nigro… - Retrovirology, 2007 - Springer
In 1871, the observation of yellowish nodules in the enlarged spleen of a cow was
considered to be the first reported case of bovine leukemia. The etiological agent of this …

Viral immune evasion: a masterpiece of evolution

MT Vossen, EM Westerhout, C Söderberg-Nauclér… - Immunogenetics, 2002 - Springer
Coexistence of viruses and their hosts imposes an evolutionary pressure on both the virus
and the host immune system. On the one hand, the host has developed an immune system …

Cattle Infected with Bovine Leukaemia Virus may not only Develop Persistent B‐cell Lymphocytosis but also Persistent B‐cell Lymphopenia

J Beyer, B Köllner, JP Teifke, E Starick… - Journal of Veterinary …, 2002 - Wiley Online Library
We investigated the distribution of B and T cells in the peripheral blood of haematologically
inconspicuous (non‐persistent lymphocytotic, PL−) cattle infected with the bovine leukaemia …

[HTML][HTML] Effect of infection with bovine leukemia virus on milk production in Michigan dairy cows

B Norby, PC Bartlett, TM Byrem, RJ Erskine - Journal of dairy science, 2016 - Elsevier
The objective of this study was to determine the association between individual cow-level
milk production and bovine leukemia virus (BLV) infection as measured by milk BLV-ELISA …

Host immune responses in the course of bovine leukemia virus infection

H KABEYA, K OHASHI, M ONUMA - Journal of Veterinary Medical …, 2001 - jstage.jst.go.jp
Bovine leukemia virus (BLV) is a type C retrovirus infecting bovine B cells and causing
enzootic bovine leukosis. Since it takes long periods to develop the disease, it is believed …

Development of an ELISA for bovine IL-10

LS Kwong, JC Hope, ML Thom, P Sopp… - Veterinary immunology …, 2002 - Elsevier
The objective of the study was to develop an assay for bovine IL-10 that could be applied to
analyses of immune responses and advance understanding of a variety of diseases of cattle …

The rapid quantitative analysis of bovine cytokine genes by real-time RT-PCR

S Konnai, T Usui, K Ohashi, M Onuma - Veterinary microbiology, 2003 - Elsevier
For a practical need, fast and efficient methods to quantify mRNA expression are expecting.
By using real-time reverse transcription polymerase chain reaction (RT-PCR) with the …

Cattle with the BoLA class II DRB3* 0902 allele have significantly lower bovine leukemia proviral loads

T Hayashi, H Mekata, S Sekiguchi, Y Kirino… - Journal of Veterinary …, 2017 - jstage.jst.go.jp
The bovine MHC (BoLA) class II DRB3 alleles are associated with polyclonal expansion of
lymphocytes caused by bovine leukemia virus (BLV) infection in cattle. To examine whether …

Upregulation of Cytokines Is Detected in the Placentas of Cattle Infected with Neospora caninum and Is More Marked Early in Gestation When Fetal Death Is …

A Rosbottom, EH Gibney, CS Guy, A Kipar… - Infection and …, 2008 - Am Soc Microbiol
The protozoan parasite Neospora caninum causes fetal death after experimental infection of
pregnant cattle in early gestation, but the fetus survives a similar infection in late gestation …

Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

R Ikebuchi, S Konnai, T Shirai, Y Sunden, S Murata… - Veterinary …, 2011 - Springer
The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-
ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens …