Drug nanoparticles embedded in a dispersant matrix as a secondary phase, ie, drug-laden
nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and …

The poor solubility of significant number of Active Pharmaceutical Ingredients (APIs) has
become a major challenge in the drug development process. Drugs with poor solubility are …

Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug
delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet …

Poor solubility of drug compounds is a great issue in drug industry today and decreasing
particle size is one efficient and simple way to overcome this challenge. Drug nanocrystals …

Low aqueous solubility of active pharmaceutical ingredients presents a serious challenge in
the development process of new drug products. This article provides an overview on some …

Process intensification (PI) is a strategy aimed at transforming conventional chemical
processes into more economical, productive and green processes. Its fundamental concept …

Science and technology have always been the vitals of human's struggle, utilized
exclusively for the development of novel tools and products, ranging from micro-to nanosize …

Solvent-free β-carotene high loaded microcapsules formulated by octenyl succinic
anhydride (OSA)-starch and trehalose were prepared by a combination of wet-milling and …

Wet media milling is a popular technology used to prepare nanosuspensions. However, the
theories and methods to guide the research on the formulation and process affecting wet …

Drug nanocrystals are nanosized solid drug particles, the most important application of
which is the improvement of solubility properties of poorly soluble drug materials. Drug …