Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Non-invasive enhancement of intracortical solute clearance using transcranial focused ultrasound

SS Yoo, E Kim, K Kowsari, J Van Reet, HC Kim… - Scientific reports, 2023 - nature.com
Transport of interstitial fluid and solutes plays a critical role in clearing metabolic waste from
the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote …

[HTML][HTML] Focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally …

JU Mascotte-Cruz, A Vera, L Leija, FE Lopez-Salas… - Discover Nano, 2024 - Springer
Neurotensin-polyplex nanoparticles provide efficient gene transfection of nigral
dopaminergic neurons when intracerebrally injected in preclinical trials of Parkinson's …

Research progress of neurovascular units involved in ischemic stroke

Y Yang, H Tong, ZF Ye, ZC Xu, T Tao - Ibrain, 2024 - Wiley Online Library
Ischemic stroke is the most prevalent cerebrovascular disorder in the clinical setting. It
results in associated neurological abnormalities due to a variety of factors, including …

[PDF][PDF] Envío dirigido de genes por vía intranasal y sanguínea a neuronas dopaminérgicas utilizando las nanopartículas de NTS-poliplex y ultrasonido focalizado en la …

JU Mascotte Cruz - 2024 - repositorio.cinvestav.mx
En ensayos preclínicos de la enfermedad de Parkinson, se ha demostrado que las
nanopartículas de poliplex de neurotensina actúan como vectores eficientes para la …