Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis

IP Trougakos, E Terpos, H Alexopoulos… - Trends in Molecular …, 2022 - cell.com
Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19)
pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is …

Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …

Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19

HM Al‐kuraishy, NR Hussien… - Immunity …, 2023 - Wiley Online Library
Introduction Covid‐19 is linked with the development of cardio‐metabolic disorders,
including dyslipidemia, dysregulation of high‐density lipoprotein (HDL), and low‐density …

Good cholesterol gone bad? HDL and COVID-19

GEG Kluck, JA Yoo, EH Sakarya, BL Trigatti - International journal of …, 2021 - mdpi.com
The transmissible respiratory disease COVID-19, caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide since its …

Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

A Luchini, S Micciulla, G Corucci, KC Batchu… - Scientific reports, 2021 - nature.com
SARS-CoV-2 spike proteins are responsible for the membrane fusion event, which allows
the virus to enter the host cell and cause infection. This process starts with the binding of the …

Progressive membrane-binding mechanism of SARS-CoV-2 variant spike proteins

M Overduin, TA Kervin, A Tran - Iscience, 2022 - cell.com
Membrane recognition by viral spike proteins is critical for infection. Here we show the host
cell membrane-binding surfaces of severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Mechanism of surfactant interactions with feline coronavirus: A physical chemistry perspective

H Mateos, A Mallardi, M Camero, G Lanave… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis Surfactants are inexpensive chemicals with promising applications in virus
inactivation, particularly for enveloped viruses. Yet, the detailed mechanisms by which …

[HTML][HTML] High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner

Y Correa, R Del Giudice, S Waldie, M Thépaut… - Journal of Colloid and …, 2023 - Elsevier
There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular
high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is …

Evaporation dynamics of a surrogate respiratory droplet in a vortical environment

S Sharma, S Jain, A Saha, S Basu - Journal of Colloid and Interface …, 2022 - Elsevier
Hypothesis Vortex droplet interaction is crucial for understanding the route of disease
transmission through expiratory jet where several such embedded droplets continuously …