The DNA-packaging nanomotor of tailed bacteriophages

SR Casjens - Nature Reviews Microbiology, 2011 - nature.com
Tailed bacteriophages use nanomotors, or molecular machines that convert chemical
energy into physical movement of molecules, to insert their double-stranded DNA genomes …

Mechanisms of DNA packaging by large double-stranded DNA viruses

VB Rao, M Feiss - Annual review of virology, 2015 - annualreviews.org
Translocation of viral double-stranded DNA (dsDNA) into the icosahedral prohead shell is
catalyzed by TerL, a motor protein that has ATPase, endonuclease, and translocase …

[HTML][HTML] Automated classification of tailed bacteriophages according to their neck organization

A Lopes, P Tavares, MA Petit, R Guérois, S Zinn-Justin - BMC genomics, 2014 - Springer
Background The genetic diversity observed among bacteriophages remains a major
obstacle for the identification of homologs and the comparison of their functional modules. In …

[HTML][HTML] Bacteriophage T4 head: structure, assembly, and genome packaging

VB Rao, A Fokine, Q Fang, Q Shao - Viruses, 2023 - mdpi.com
Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological
structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …

[HTML][HTML] The structure of the phage T4 DNA packaging motor suggests a mechanism dependent on electrostatic forces

S Sun, K Kondabagil, B Draper, TI Alam, VD Bowman… - Cell, 2008 - cell.com
Viral genomes are packaged into" procapsids" by powerful molecular motors. We report the
crystal structure of the DNA packaging motor protein, gene product 17 (gp17), in …

Genome packaging in viruses

S Sun, VB Rao, MG Rossmann - Current opinion in structural biology, 2010 - Elsevier
Genome packaging is a fundamental process in a viral life cycle. Many viruses assemble
preformed capsids into which the genomic material is subsequently packaged. These …

The bacteriophage DNA packaging machine

M Feiss, VB Rao - Viral molecular machines, 2011 - Springer
Large dsDNA bacteriophages and herpesviruses encode a powerful ATP-driven DNA-
translocating machine that encapsidates a viral genome into a preformed capsid shell or …

[HTML][HTML] Viral small terminase: A divergent structural framework for a conserved biological function

RK Lokareddy, CFD Hou, F Li, R Yang, G Cingolani - Viruses, 2022 - mdpi.com
The genome packaging motor of bacteriophages and herpesviruses is built by two
terminase subunits, known as large (TerL) and small (TerS), both essential for viral genome …

[HTML][HTML] Structure and assembly of bacteriophage T4 head

VB Rao, LW Black - Virology journal, 2010 - Springer
The bacteriophage T4 capsid is an elongated icosahedron, 120 nm long and 86 nm wide,
and is built with three essential proteins; gp23*, which forms the hexagonal capsid lattice …

Structure, assembly, and DNA packaging of the bacteriophage T4 head

LW Black, VB Rao - Advances in virus research, 2012 - Elsevier
The bacteriophage T4 head is an elongated icosahedron packed with 172 kb of linear
double-stranded DNA and numerous proteins. The capsid is built from three essential …