Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels
In recent years, dynamic,'click'hydrogels have been applied in numerous biomedical
applications. Owing to the mild, cytocompatible, and highly specific reaction kinetics, a …
applications. Owing to the mild, cytocompatible, and highly specific reaction kinetics, a …
Designer self‐assembling peptide hydrogels to engineer 3D cell microenvironments for cell constructs formation and precise oncology remodeling in ovarian cancer
Z Yang, H Xu, X Zhao - Advanced Science, 2020 - Wiley Online Library
Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …
[HTML][HTML] Effect of polymeric matrix stiffness on osteogenic differentiation of mesenchymal stem/progenitor cells: concise review
Mesenchymal stem/progenitor cells (MSCs) have a multi-differentiation potential into
specialized cell types, with remarkable regenerative and therapeutic results. Several factors …
specialized cell types, with remarkable regenerative and therapeutic results. Several factors …
Dynamic modulation of matrix adhesiveness induces epithelial-to-mesenchymal transition in prostate cancer cells in 3D
Synthetic matrices with dynamic presentation of cell guidance cues are needed for the
development of physiologically relevant in vitro tumor models. Towards the goal of …
development of physiologically relevant in vitro tumor models. Towards the goal of …
Matrix adhesiveness regulates myofibroblast differentiation from vocal fold fibroblasts in a bio-orthogonally cross-linked hydrogel
Repeated mechanical and chemical insults cause an irreversible alteration of extracellular
matrix (ECM) composition and properties, giving rise to vocal fold scarring that is refractory …
matrix (ECM) composition and properties, giving rise to vocal fold scarring that is refractory …
Click-functionalized hydrogel design for mechanobiology investigations
The advancement of click-functionalized hydrogels in recent years has coincided with rapid
growth in the fields of mechanobiology, tissue engineering, and regenerative medicine …
growth in the fields of mechanobiology, tissue engineering, and regenerative medicine …
Dynamic click hydrogels for xeno‐free culture of induced pluripotent stem cells
MR Arkenberg, NH Dimmitt, HC Johnson… - Advanced …, 2020 - Wiley Online Library
Xeno‐free, chemically defined poly (ethylene glycol)(PEG)‐based hydrogels are being
increasingly used for in vitro culture and differentiation of human induced pluripotent stem …
increasingly used for in vitro culture and differentiation of human induced pluripotent stem …
Hydrogels to Recapture Extracellular Matrix Cues That Regulate Vascularization
The ECM (extracellular matrix) is a 3-dimensional network that supports cellular responses
and maintains structural tissue integrity in healthy and pathological conditions. The …
and maintains structural tissue integrity in healthy and pathological conditions. The …
Tetrazine-Mediated Bioorthogonal System for Prodrug Activation, Photothermal Therapy, and Optoacoustic Imaging
Bioorthogonal “bond cleavage” reactions hold great promise in a variety of biological
applications such as controlled activation of the drug and probe, while the application of …
applications such as controlled activation of the drug and probe, while the application of …