Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

Copper is a required micronutrient for bacteria and an essential cofactor for redox‐active
cuproenzymes. Yet, excess copper is extremely toxic, and is exploited as a bacteriocide in …

Copper is an essential micronutrient for most organisms that is required as a cofactor for
crucial copper-dependent enzymes encoded by both prokaryotes and eukaryotes. Evidence …

The mucophilic anaerobic bacterium Akkermansia muciniphila is a prominent member of the
gastrointestinal (GI) microbiota and the only known species of the Verrucomicrobia phylum …

The bacterial cell envelope is a protective barrier at the frontline of bacterial interaction with
the environment, and its integrity is regulated by various stress response systems. The Rcs …

Gram-negative bacteria resist external stresses due to cell envelope rigidity, which is
provided by two membranes and a peptidoglycan layer. The outer membrane (OM) surface …

Highlights•A network of biogenesis pathways builds the Gram-negative bacterial cell
envelope.•ESRs monitor envelope integrity and biogenesis during normal growth and …

Bacterial lipoproteins are globular proteins anchored to a membrane by a lipid moiety. By
discovering new functions carried out by lipoproteins, recent research has highlighted the …

Copper avidly binds thiols and is redox active, and it follows that one element of copper
toxicity may be the generation of undesirable disulfide bonds in proteins. In the present …

The global public health burden of bacterial antimicrobial resistance (AMR) is intensified by
Gram-negative bacteria, which have an additional membrane, the outer membrane (OM) …