[Retracted] Noscapine, an Emerging Medication for Different Diseases: A Mechanistic Review

P Rahmanian-Devin… - Evidence‐Based …, 2021 - Wiley Online Library
Noscapine is a benzylisoquinoline alkaloid isolated from poppy extract, used as an
antitussive since the 1950s, and has no addictive or euphoric effects. Various studies have …

Papaver Plants: Current Insights on Phytochemical and Nutritional Composition Along with Biotechnological Applications

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
The genus Papaver is highly esteemed in the pharmacy industry, in the culinary field, and as
ornamental plants. These plants are also valued in traditional medicine. Among all Papaver …

A review of recent advances in quinoline/isoquinoline based hybrids as microtubule targeted cancer therapeutics: Synthesis, binding mode, QSAR and docking …

P Nasehi, N Omidkhah, R Ghodsi - Journal of Molecular Structure, 2023 - Elsevier
Tubulin, an important clinical molecular target, has attracted high attention in drug design
development and cancer treatment. Tubulin inhibitors cause cell cycle arrest in the G 2/M …

[HTML][HTML] New trends in the practical use of isoquinoline alkaloids as potential drugs applicated in infectious and non-infectious diseases

T Tuzimski, A Petruczynik - Biomedicine & Pharmacotherapy, 2023 - Elsevier
In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …

Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids

F Subrizi, Y Wang, B Thair… - Angewandte Chemie …, 2021 - Wiley Online Library
The tetrahydroisoquinoline (THIQ) ring system is present in a large variety of structurally
diverse natural products exhibiting a wide range of biological activities. Routes to mimic the …

[HTML][HTML] A review of research progress of antitumor drugs based on tubulin targets

Z Cheng, X Lu, B Feng - Translational cancer research, 2020 - ncbi.nlm.nih.gov
Microtubules exist in all eukaryotic cells and are one of the critical components that make up
the cytoskeleton. Microtubules play a crucial role in supporting cell morphology, cell division …

[HTML][HTML] Unraveling the role of chitosan for nasal drug delivery systems: A review

G Kaur, J Goyal, PK Behera, S Devi, SK Singh… - Carbohydrate Polymer …, 2023 - Elsevier
The discipline of nanoscience has made enormous strides in the recent two decades. The
researchers in the field of nanomedicine have been looking into using natural …

Dysregulation of microtubule nucleating proteins in cancer cells

P Dráber, E Dráberová - Cancers, 2021 - mdpi.com
Simple Summary The dysfunction of microtubule nucleation in cancer cells changes the
overall cytoskeleton organization and cellular physiology. This review focuses on the …

[HTML][HTML] Advances in glioblastoma multiforme: Integrating therapy and pathology perspectives

SH Shahcheraghi, M Alimardani, M Lotfi, M Lotfi… - … -Research and Practice, 2024 - Elsevier
Glioblastoma, a highly lethal form of brain cancer, is characterized by its aggressive growth
and resistance to conventional treatments, often resulting in limited survival. The response to …

An overview of natural and synthetic phthalides involved in cancer studies: Past, present, and future

BC Sadıkoğulları, P Şenel, N Çini, AA Faysal… - …, 2022 - Wiley Online Library
Phthalides, mainly isolated from two genera: Ligusticum and Angelica of the Apiceae (syn
Umbelliferae) family, are thought to be a potent natural compound with many therapeutic …