Gastric cancer is one of the most common malignant tumours worldwide. Genetic and
epigenetic alterations are key factors in gastric carcinogenesis and drug resistance to …

SOX transcription factors are critical regulators of development, homeostasis and disease
progression and their dysregulation is a common finding in various cancers. SOX9 belongs …

Posttranscriptional modifications in RNA have been considered to contribute to disease
pathogenesis and tumor progression. NOL1/NOP2/Sun domain family member 2 (NSUN2) …

Gastric cancer (GC) is a leading cause of death worldwide. GC is the third-most common
cause of cancer-related death after lung and colorectal cancer. It is also the fifth-most …

Glioblastoma (GBM) is the most common, most aggressive and deadliest brain tumor.
Recently, remarkable progress has been made towards understanding the cellular and …

The extraordinary plasticity of glioma cells allows them to contribute to different cellular
compartments in tumor vessels, reinforcing the vascular architecture. It was recently …

Disruptions to developmental cell signaling pathways and transcriptional cascades have
been implicated in tumor initiation, maintenance and progression. Resurgence of aberrant …

Background and aims The crosstalk between cancer stem cells (CSCs) and their niche is
required for the maintenance of stem cell-like phenotypes of CSCs. Here, we identified E26 …

Brain tumors are responsible for high mortality and morbidity worldwide. The brain tumor
treatment depends on identification of molecular pathways involved in progression and …

Although oncogenicity of the stem cell regulator SOX9 has been implicated in many solid
tumors, its role in lymphomagenesis remains largely unknown. In this study, SOX9 was …