Low-energy electron damage to condensed-phase DNA and its constituents

Y Gao, Y Zheng, L Sanche - International Journal of Molecular Sciences, 2021 - mdpi.com
The complex physical and chemical reactions between the large number of low-energy (0–
30 eV) electrons (LEEs) released by high energy radiation interacting with genetic material …

Lab-on-a-DNA origami: nanoengineered single-molecule platforms

S Kogikoski, J Ameixa, A Mostafa, I Bald - Chemical Communications, 2023 - pubs.rsc.org
DNA origami nanostructures are self-assembled into almost arbitrary two-and three-
dimensional shapes from a long, single-stranded viral scaffold strand and a set of short …

The potential of DNA origami to build multifunctional materials

K Tapio, I Bald - Multifunctional Materials, 2020 - iopscience.iop.org
The development of the DNA origami technique has revolutionized the field of DNA
nanotechnology as it allows to create virtually any arbitrarily shaped nanostructure out of …

Low-energy (5–20 eV) electron-induced single and double strand breaks in well-defined DNA sequences

K Ebel, I Bald - The Journal of Physical Chemistry Letters, 2022 - ACS Publications
Ionizing radiation is used in cancer radiation therapy to effectively damage the DNA of
tumors. The main damage is due to generation of highly reactive secondary species such as …

Early events in radiobiology: Isolated and cluster DNA damage induced by initial cations and nonionizing secondary electrons

Y Dong, H Liao, Y Gao, P Cloutier… - The Journal of …, 2021 - ACS Publications
Radiobiological damage is principally triggered by an initial cation and a secondary electron
(SE). We address the fundamental questions: What lesions are first produced in DNA by this …

Folding DNA into origami nanostructures enhances resistance to ionizing radiation

L Sala, A Zerolová, A Rodriguez, D Reimitz… - Nanoscale, 2021 - pubs.rsc.org
We report experimental results on damage induced by ionizing radiation to DNA origami
triangles which are commonly used prototypes for scaffolded DNA origami nanostructures …

Ultrafast processes occurring in radiolysis of highly concentrated solutions of nucleosides/tides

J Ma, SA Denisov, A Adhikary, M Mostafavi - International Journal of …, 2019 - mdpi.com
Among the radicals (hydroxyl radical (• OH), hydrogen atom (H•), and solvated electron
(esol−)) that are generated via water radiolysis,• OH has been shown to be the main …

Quantum Yield of DNA Strand Breaks under Photoexcitation of a Molecular Ruby

C Wang, K Ebel, K Heinze… - … –A European Journal, 2023 - Wiley Online Library
Photodynamic therapy (PDT) used for treating cancer relies on the generation of highly
reactive oxygen species, for example, singlet oxygen 1O2, by light‐induced excitation of a …

Unraveling the Complexity of DNA Radiation Damage Using DNA Nanotechnology

J Ameixa, I Bald - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Radiation cancer therapies use different ionizing radiation qualities that
damage DNA molecules in tumor cells by a yet not completely understood plethora of …

Damage Induced to DNA and Its Constituents by 0–3 eV UV Photoelectrons

C Liu, Y Zheng, L Sanche - Photochemistry and Photobiology, 2022 - Wiley Online Library
The complex physical and chemical interactions between DNA and 0–3 eV electrons
released by UV photoionization can lead to the formation of various lesions such as base …