Background: The management of chronic rhinosinusitis with nasal polyps (CRSwNP) is
evolving, with an emphasis on treating the underlying type 2 inflammation. Objective: The …

Introduction Staphylococcus aureus (S. aureus) is a common pathogen that frequently
colonizes the sinonasal cavity. Recent studies demonstrated the essential role of …

Introduction: Chronic rhinosinusitis is a common condition characterized by inflammation of
the nasal and sinus linings, rhinorrhea, nasal blockage, facial pain, and loss of sense of …

Various chronic inflammatory airway diseases can be treated with low-dose, long-term
(LDLT) macrolide therapy. LDLT macrolides can be one of the therapeutic options for …

Background Remission, defined as absence of symptoms and objective markers of disease,
is emerging as the penultimate goal in the management of several chronic diseases. The …

Objective Previous in vitro transcriptomic profiling suggests azithromycin exerts its effects in
patients with chronic rhinosinusitis (CRS) via modulation of type 1 inflammation and …

Objectives Successful recovery from chronic rhinosinusitis (CRS) following endoscopic
sinus surgery (ESS) can be characterized by minimal presence of symptoms and absence of …

Justification We have previously documented that in individuals with chronic rhinosinusitis
(CRS) refractory to surgery, intranasal application of live Lactococcus lactis W136, a …

Background Identifying effective therapy for recalcitrant chronic rhinosinusitis with nasal
polyposis (CRSwNP) is a major challenge; and subtypes such as aspirin-exacerbated …

Nnabue et al. 16 used histological techniques and high-resolution confocal microscopy to
demonstrate a significant decrease in gland density in the posterior septum of patients with …