The pathogenesis of Parkinson's disease (PD) is complex, multilayered, and not fully
understood, resulting in a lack of effective disease-modifying treatments for this prevalent …

Klotho, which is a life extension factor, and erythropoietin (EPO) have been introduced as
effective neuroprotective factors in several neurological disorders. The present study is an …

Klotho, as an antiaging protein, is involved in the maintenance and differentiation of
neuronal or glial cells and, therefore, has been noticed as a potential therapeutic target for …

Abstract Treatment of multiple sclerosis (MS) remains a major challenge. The aim of this
study was to evaluate the therapeutic potential of mesenchymal stem cells (MSCs) …

Experimental autoimmune encephalomyelitis is a demyelinating disease that causes
paralysis in laboratory rats. This condition lacks treatment that reverses damage to the …

Objective to explore the status of concentration of klotho and fibroblast growth factor 23
(FGF23) in cerebrospinal fluid (CSF) of patients with narcolepsy. Patients/methods 59 …

Exercise has been shown to increase myelin biomarkers such as klotho and PLP and
improve clinical and pathological symptoms using the experimental autoimmune …

Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelination
disease associated with inflammatory reactions and attenuation of antioxidant capacity …

Background Purpose Exercise activity plays an important role in increasing biomarkers such
as Klotho and PLP and improves clinical outcome in mice with MS. In the present study, we …

Nowadays, many studies have shown that exercise improves brain health and performance
and may also increase neurological pathways in the brain. The aim of the present study was …