Microfluidic systems for single DNA dynamics
DJ Mai, C Brockman, CM Schroeder - Soft matter, 2012 - pubs.rsc.org
Recent advances in microfluidics have enabled the molecular-level study of polymer
dynamics using single DNA chains. Single polymer studies based on fluorescence …
dynamics using single DNA chains. Single polymer studies based on fluorescence …
Recent advances in single‐molecule detection on micro‐and nano‐fluidic devices
C Liu, Y Qu, Y Luo, N Fang - Electrophoresis, 2011 - Wiley Online Library
Single‐molecule detection (SMD) allows static and dynamic heterogeneities from seemingly
equal molecules to be revealed in the studies of molecular structures and intra‐and inter …
equal molecules to be revealed in the studies of molecular structures and intra‐and inter …
Multiplexed miRNA quantitation using injectionless microfluidic thermal gel electrophoresis
MA Cornejo, TH Linz - Analytical chemistry, 2022 - ACS Publications
MicroRNAs (miRNAs) are a class of biomolecules that have high clinical and
pharmaceutical significance because of their ability to regulate protein expression. Better …
pharmaceutical significance because of their ability to regulate protein expression. Better …
Micronozzle array enhanced sandwich electroporation of embryonic stem cells
Electroporation is one of the most popular nonviral gene transfer methods for embryonic
stem cell transfection. Bulk electroporation techniques, however, require a high electrical …
stem cell transfection. Bulk electroporation techniques, however, require a high electrical …
[HTML][HTML] Microfluidic converging/diverging channels optimised for homogeneous extensional deformation
In this work, we optimise microfluidic converging/diverging geometries in order to produce
constant strain-rates along the centreline of the flow, for performing studies under …
constant strain-rates along the centreline of the flow, for performing studies under …
The use of microfluidics in rheology
X Hu, PE Boukany, OL Hemminger… - Macromolecular …, 2011 - Wiley Online Library
The combination of microfluidics and fluorescent‐labeled DNA molecules in rheology
provides a unique opportunity to relate the microstructure of polymer molecules to their …
provides a unique opportunity to relate the microstructure of polymer molecules to their …
Optimization of flow-focusing devices for homogeneous extensional flow
We present a methodology for the shape optimization of flow-focusing devices with the
purpose of creating a wide region of homogeneous extensional flow, characterized by a …
purpose of creating a wide region of homogeneous extensional flow, characterized by a …
Effect of the electrostatic interactions on stretching of semiflexible and biological polyelectrolytes
JMY Carrillo, AV Dobrynin - Macromolecules, 2010 - ACS Publications
Using combination of the molecular dynamics simulations and theoretical calculations, we
have demonstrated that the bending rigidity of biological polyelectrolytes (semiflexible …
have demonstrated that the bending rigidity of biological polyelectrolytes (semiflexible …
Simulation of conformational preconditioning strategies for electrophoretic stretching of DNA in a microcontraction
CC Hsieh, TH Lin - Biomicrofluidics, 2011 - pubs.aip.org
We have used Brownian dynamics-finite element method to examine two conformational
preconditioning approaches for improving DNA stretching in a microcontraction for the …
preconditioning approaches for improving DNA stretching in a microcontraction for the …
Development of Microfluidic Thermal Gel Electrophoresis for Biological Analysis
MA Cornejo - 2024 - search.proquest.com
The molecular biology that takes place within cells is vital to the overall function of an
organism. Healthy cellular function is crucial to a wide web of interconnected processes that …
organism. Healthy cellular function is crucial to a wide web of interconnected processes that …