Decellularized matrices in regenerative medicine
Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …
promising tool used either alone or when combined with other biologics in the fields of tissue …
Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function
BLM Hogan, CE Barkauskas, HA Chapman, JA Epstein… - Cell stem cell, 2014 - cell.com
Respiratory disease is the third leading cause of death in the industrialized world.
Consequently, the trachea, lungs, and cardiopulmonary vasculature have been the focus of …
Consequently, the trachea, lungs, and cardiopulmonary vasculature have been the focus of …
Decellularization systems and devices: State-of-the-art
Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …
structural support to its surrounding cells, forming tissue and respective organs. These ECM …
Engineering pulmonary vasculature in decellularized rat and human lungs
Bioengineered lungs produced from patient-derived cells may one day provide an
alternative to donor lungs for transplantation therapy. Here we report the regeneration of …
alternative to donor lungs for transplantation therapy. Here we report the regeneration of …
A review of cellularization strategies for tissue engineering of whole organs
ME Scarritt, NC Pashos, BA Bunnell - Frontiers in bioengineering and …, 2015 - frontiersin.org
With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …
organ engineering were generated from numerous tissues, including the heart, lung, liver …
Extracellular matrix remodelling in COPD
M Karakioulaki, E Papakonstantinou… - European Respiratory …, 2020 - Eur Respiratory Soc
The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …
offers a low resistant pathway that allows the exchange of gases, provides compressive …
Lung regeneration: endogenous and exogenous stem cell mediated therapeutic approaches
The tissue turnover of unperturbed adult lung is remarkably slow. However, after injury or
insult, a specialised group of facultative lung progenitors become activated to replenish …
insult, a specialised group of facultative lung progenitors become activated to replenish …
Native extracellular matrix: a new scaffolding platform for repair of damaged muscle
L Teodori, A Costa, R Marzio, B Perniconi… - Frontiers in …, 2014 - frontiersin.org
Effective clinical treatments for volumetric muscle loss resulting from traumatic injury or
resection of a large amount of muscle mass are not available to date. Tissue engineering …
resection of a large amount of muscle mass are not available to date. Tissue engineering …
Advances in the knowledge about kidney decellularization and repopulation
AC Destefani, GM Sirtoli, BV Nogueira - Frontiers in bioengineering …, 2017 - frontiersin.org
End-stage renal disease (ESRD) is characterized by the progressive deterioration of renal
function that may compromise different tissues and organs. The major treatment indicated for …
function that may compromise different tissues and organs. The major treatment indicated for …
Unravelling the molecular mechanisms underlying chronic respiratory diseases for the development of novel therapeutics via in vitro experimental models
Chronic respiratory diseases have collectively become a major public health concern and
have now taken form as one of the leading causes of mortality worldwide. Most chronic …
have now taken form as one of the leading causes of mortality worldwide. Most chronic …