Cancer recurrence and drug resistance following treatment, as well as metastatic forms of
cancer, are trends that are commonly encountered in cancer management. Amidst the …

Extracellular vesicles (EVs) are being widely investigated as acellular therapeutics in
regenerative medicine applications. EVs isolated from mesenchymal stromal cells (MSCs) …

The concept of dedifferentiation and reprogramming of mature somatic cells holds much
promise for the three-front “war” against tissue damage, cancer, and aging. It was hoped that …

Human induced pluripotent stem cells (iPSCs) provide a virtually inexhaustible source of
starting material for next generation cell therapies, offering new opportunities for …

Stem cell–based cell therapeutics and especially those based on human mesenchymal
stem cells (hMSCs) and induced pluripotent stem cells (hiPSCs) are said to have enormous …

Cerebral ischemia impedes the functional or metabolic demands of the central nervous
system (CNS), which subsequently leads to irreversible brain damage. While recanalization …

Mesenchymal stem/stromal cells (MSCs) show tremendous potential for regenerative
medicine due to their self-renewal, multi-differentiation and immunomodulatory capabilities …

Mesenchymal stem/stromal cells (MSC) are well known for immunomodulation; however, the
mechanisms involved in their benefits in the ischemic retina are unknown. This study tested …

Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously reduces the patient's quality of
life, yet current therapies only provide partial relief. In the spinal dorsal horn (SDH) …

Smooth muscle cells (SMCs) are the main functional component of urethral tissue, but are
difficult to proliferate in vitro. Mesenchymal stem cells (MSCs) and mesenchymal stem cell …